Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4125046..4125191 Replicon chromosome
Accession NZ_CP069961
Organism Klebsiella pneumoniae strain FDAARGOS_1317

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4125082..4125184 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4125046..4125191 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K47_RS19985 4120176..4122236 + 2061 WP_004151449.1 oligopeptidase B -
I6K47_RS19990 4122240..4122899 - 660 WP_002911407.1 exodeoxyribonuclease X -
I6K47_RS19995 4122978..4123208 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K47_RS20000 4123321..4123695 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K47_RS20005 4123699..4124568 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
I6K47_RS20010 4124585..4124923 + 339 WP_002911404.1 YebY family protein -
- 4125046..4125191 - 146 - - Antitoxin
- 4125082..4125184 + 103 - - Toxin
I6K47_RS20015 4125559..4125702 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I6K47_RS20020 4125807..4126775 - 969 WP_014907334.1 VirK/YbjX family protein -
I6K47_RS20025 4126932..4127585 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
I6K47_RS20030 4127582..4127773 - 192 WP_002911395.1 YebW family protein -
I6K47_RS20035 4127871..4128110 - 240 WP_002911393.1 YebV family protein -
I6K47_RS20040 4128226..4129659 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192331 NZ_CP069961:4125082-4125184 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192331 NZ_CP069961:c4125191-4125046 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References