Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1537469..1537614 Replicon chromosome
Accession NZ_CP069946
Organism Klebsiella pneumoniae strain FDAARGOS_1325

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1537476..1537578 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1537469..1537614 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K55_RS07635 1533000..1534433 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K55_RS07640 1534549..1534788 + 240 WP_002911393.1 YebV family protein -
I6K55_RS07645 1534886..1535077 + 192 WP_002911395.1 YebW family protein -
I6K55_RS07650 1535074..1535727 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
I6K55_RS07655 1535884..1536852 + 969 WP_014907334.1 VirK/YbjX family protein -
I6K55_RS07660 1536957..1537100 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 1537469..1537614 + 146 - - Antitoxin
- 1537476..1537578 - 103 - - Toxin
I6K55_RS07665 1537737..1538075 - 339 WP_002911404.1 YebY family protein -
I6K55_RS07670 1538092..1538961 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
I6K55_RS07675 1538965..1539339 - 375 WP_039819395.1 CopC domain-containing protein YobA -
I6K55_RS07680 1539452..1539682 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K55_RS07685 1539761..1540420 + 660 WP_002911407.1 exodeoxyribonuclease X -
I6K55_RS07690 1540424..1542484 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192252 NZ_CP069946:c1537578-1537476 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192252 NZ_CP069946:1537469-1537614 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References