Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 456238..456383 Replicon chromosome
Accession NZ_CP069940
Organism Klebsiella pneumoniae strain FDAARGOS_1312

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 456245..456347 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 456238..456383 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K42_RS02285 451770..453203 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K42_RS02290 453319..453558 + 240 WP_002911393.1 YebV family protein -
I6K42_RS02295 453656..453847 + 192 WP_002911395.1 YebW family protein -
I6K42_RS02300 453844..454497 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
I6K42_RS02305 454654..455622 + 969 WP_014907334.1 VirK/YbjX family protein -
I6K42_RS02310 455727..455870 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 456238..456383 + 146 - - Antitoxin
- 456245..456347 - 103 - - Toxin
I6K42_RS02315 456506..456844 - 339 WP_002911404.1 YebY family protein -
I6K42_RS02320 456861..457730 - 870 WP_014907333.1 copper homeostasis membrane protein CopD -
I6K42_RS02325 457734..458108 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K42_RS02330 458221..458451 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K42_RS02335 458530..459189 + 660 WP_002911407.1 exodeoxyribonuclease X -
I6K42_RS02340 459193..461253 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192188 NZ_CP069940:c456347-456245 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192188 NZ_CP069940:456238-456383 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References