Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1877648..1877793 Replicon chromosome
Accession NZ_CP069907
Organism Klebsiella pneumoniae strain FDAARGOS_1313

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1877655..1877757 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1877648..1877793 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K43_RS12255 1873179..1874612 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K43_RS12260 1874728..1874967 + 240 WP_002911393.1 YebV family protein -
I6K43_RS12265 1875065..1875256 + 192 WP_002911395.1 YebW family protein -
I6K43_RS12270 1875253..1875906 - 654 WP_048982385.1 protein-serine/threonine phosphatase -
I6K43_RS12275 1876063..1877031 + 969 WP_004151446.1 VirK/YbjX family protein -
I6K43_RS12280 1877136..1877279 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1877648..1877793 + 146 - - Antitoxin
- 1877655..1877757 - 103 - - Toxin
I6K43_RS12285 1877916..1878254 - 339 WP_048982383.1 YebY family protein -
I6K43_RS12290 1878271..1879140 - 870 WP_023285313.1 copper homeostasis membrane protein CopD -
I6K43_RS12295 1879144..1879518 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K43_RS12300 1879631..1879861 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K43_RS12305 1879940..1880599 + 660 WP_002911407.1 exodeoxyribonuclease X -
I6K43_RS12310 1880603..1882663 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T192112 NZ_CP069907:c1877757-1877655 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT192112 NZ_CP069907:1877648-1877793 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References