Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3971496..3971730 | Replicon | chromosome |
| Accession | NZ_CP069882 | ||
| Organism | Escherichia coli strain FDAARGOS_1289 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3971497..3971600 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3971496..3971730 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6K19_RS19100 | 3968444..3969496 | + | 1053 | WP_021517972.1 | RecT family recombinase | - |
| I6K19_RS19105 | 3969560..3969754 | + | 195 | WP_021500490.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| I6K19_RS19110 | 3969747..3969935 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 3969753..3969931 | - | 179 | NuclAT_0 | - | - |
| - | 3969753..3969931 | - | 179 | NuclAT_0 | - | - |
| - | 3969753..3969931 | - | 179 | NuclAT_0 | - | - |
| - | 3969753..3969931 | - | 179 | NuclAT_0 | - | - |
| I6K19_RS19115 | 3970042..3970323 | + | 282 | WP_001311878.1 | excisionase | - |
| I6K19_RS19120 | 3970289..3971365 | + | 1077 | WP_021517971.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 3971496..3971730 | + | 235 | - | - | Antitoxin |
| - | 3971497..3971600 | - | 104 | - | - | Toxin |
| I6K19_RS19125 | 3971758..3972099 | - | 342 | WP_000976481.1 | YebY family protein | - |
| I6K19_RS19130 | 3972112..3972984 | - | 873 | WP_000879330.1 | copper homeostasis membrane protein CopD | - |
| I6K19_RS19135 | 3972988..3973362 | - | 375 | WP_000204705.1 | CopC domain-containing protein YobA | - |
| I6K19_RS19140 | 3973501..3973731 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| I6K19_RS19145 | 3973833..3974489 | + | 657 | WP_000011651.1 | carbon-nitrogen hydrolase family protein YobB | - |
| I6K19_RS19150 | 3974513..3975175 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 3921605..3979040 | 57435 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T192018 NZ_CP069882:c3971600-3971497 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT192018 NZ_CP069882:3971496-3971730 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
