Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4960792..4960937 Replicon chromosome
Accession NZ_CP069873
Organism Klebsiella pneumoniae strain FDAARGOS_1323

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4960799..4960901 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4960792..4960937 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6K53_RS23890 4956324..4957757 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6K53_RS23895 4957873..4958112 + 240 WP_002911393.1 YebV family protein -
I6K53_RS23900 4958210..4958401 + 192 WP_002911395.1 YebW family protein -
I6K53_RS23905 4958398..4959051 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
I6K53_RS23910 4959208..4960176 + 969 WP_004151446.1 VirK/YbjX family protein -
I6K53_RS23915 4960281..4960424 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 4960792..4960937 + 146 - - Antitoxin
- 4960799..4960901 - 103 - - Toxin
I6K53_RS23920 4961060..4961398 - 339 WP_002911404.1 YebY family protein -
I6K53_RS23925 4961415..4962284 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
I6K53_RS23930 4962288..4962662 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6K53_RS23935 4962775..4963005 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6K53_RS23940 4963084..4963743 + 660 WP_032435029.1 exodeoxyribonuclease X -
I6K53_RS23945 4963747..4965807 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T191990 NZ_CP069873:c4960901-4960799 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT191990 NZ_CP069873:4960792-4960937 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References