Detailed information of TA system TA191802

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-RelB
• Location: 1169481..1169995
• Replicon: chromosome
• Accession: NZ_CP069798
• Organism: Paralysiella testudinis strain 26B

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JQU52_RS06020
• Protein ID: WP_230340230.1
• Coordinates: 1169481..1169744 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JQU52_RS06025
• Protein ID: WP_230340231.1
• Coordinates: 1169741..1169995 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JQU52_RS05990 (JQU52_06020)	1165548..1166210	+	663	WP_230340224.1	7-cyano-7-deazaguanine synthase QueC	-
JQU52_RS05995 (JQU52_06025)	1166207..1166641	+	435	WP_230340225.1	6-carboxytetrahydropterin synthase QueD	-
JQU52_RS06000 (JQU52_06030)	1166634..1167248	+	615	WP_230340226.1	7-carboxy-7-deazaguanine synthase QueE	-
JQU52_RS06005 (JQU52_06035)	1167542..1167811	+	270	WP_230340227.1	DUF493 family protein	-
JQU52_RS06010 (JQU52_06040)	1167811..1168416	+	606	WP_230340228.1	lipoyl(octanoyl) transferase LipB	-
JQU52_RS06015 (JQU52_06045)	1168449..1169402	+	954	WP_230340229.1	lipoyl synthase	-
JQU52_RS06020 (JQU52_06050)	1169481..1169744	-	264	WP_230340230.1	Txe/YoeB family addiction module toxin	Toxin
JQU52_RS06025 (JQU52_06055)	1169741..1169995	-	255	WP_230340231.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
JQU52_RS06030 (JQU52_06060)	1170244..1171641	-	1398	WP_230340232.1	ethanolamine permease	-
JQU52_RS06035 (JQU52_06065)	1171745..1172272	-	528	WP_230340233.1	DinB family protein	-
JQU52_RS06040 (JQU52_06070)	1172441..1173166	-	726	WP_230340234.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
JQU52_RS06045 (JQU52_06075)	1173163..1174323	-	1161	WP_230340235.1	iron-containing alcohol dehydrogenase	-
JQU52_RS06050 (JQU52_06080)	1174386..1174859	-	474	WP_230340236.1	OsmC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10631.33 Da
• Isoelectric Point: 10.3826

>T191802 WP_230340230.1 NZ_CP069798:c1169744-1169481 [Paralysiella testudinis]
MMLAWADDAWNDYMYWQQTDKRMLKRINMLLKGIQRQPFAGLGDPEPLKHNWSGFWSRRINKEHRLVYRVSNDRVMVAQC
RYHYGKL

Nucleotide

• Length: 264 bp

>T191802 NZ_CP091913:c3391302-3391006 [Nostoc sp. UHCC 0870]
ATGGGACTTAACAGTAAGCATCAAAAAACACTGGATGACATTTTTGAAAATCCCGTTAGATCCAATATTCCTTGGAGTGA
TATTGAATCTATGCTAATTGCACTTGGTGCGGAAGTGTCAGAAGGAAGGGGGTCAAGAGTGAGAATAGCTCTTAATAGCG
TAAAGGCAACTTTTCACAGGCCACACCCGGAAAAAGAAACTAATAAAGGTGCTGTTAAATCTATGCGCCGTTTCTTAACA
GAGTCCAGGGTTAAAGAAGACACGGACACGGGAGGACTTAGTGACAATGAAATATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.40 Da
• Isoelectric Point: 5.0210

>AT191802 WP_230340231.1 NZ_CP069798:c1169995-1169741 [Paralysiella testudinis]
MDTMSYSAFRAGLAGVLDKVNDNHKPVLVTRQNGKPAVVMSLEDFQSYEETAYLMASPANAERLNRAVAQIRAGEAQQHG
MLEE

Nucleotide

• Length: 255 bp

>AT191802 NZ_CP091913:c3391016-3390696 [Nostoc sp. UHCC 0870]
ATGAAATATAAAGGATATGAAGCTGTTGTGGAATTTGACGATGAAGCTGAGATTTTTCATGGCGAAGTAGTCAACCTGCG
AGATGTGATTACATTTCAGGGTGACAGCGTGAAAGAGCTAAGGCAAGCTTTCCACGACTCAGTTGATGATTATTTAGAAT
TTTGCCAAAAACGTGGCGAAGAACCTGAAAAACCATTTTCAGGTAAGCTCATGCTCAGAATTAACCCTGAATTACATAAA
ACAATTGCTATCAAAGCAAAGAAAGAGGGTCAAAGCCTTAATTCTTGGATAGAAAAATGTTTGTGTATGTATGCACCGTA
G