Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 1121615..1122060 Replicon chromosome
Accession NZ_CP069798
Organism Paralysiella testudinis strain 26B

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag JQU52_RS05765 Protein ID WP_230340183.1
Coordinates 1121842..1122060 (+) Length 73 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag JQU52_RS05760 Protein ID WP_230340173.1
Coordinates 1121615..1121845 (+) Length 77 a.a.

Genomic Context

JQU52_RS05730JQU52_RS05740JQU52_RS05755JQU52_RS05760JQU52_RS05765JQU52_RS05775JQU52_RS05780JQU52_RS05785JQU52_RS05790JQU52_RS05795JQU52_RS05800JQU52_RS05805JQU52_RS05810JQU52_RS05745JQU52_RS05750
Location: 1116849..1117532 (684 bp)
Type: Others
Protein ID: WP_230340178.1
Location: 1118647..1118817 (171 bp)
Type: Others
Protein ID: WP_230340179.1
Location: 1120270..1120917 (648 bp)
Type: Others
Protein ID: WP_230340182.1
Location: 1121615..1121845 (231 bp)
Type: Antitoxin
Protein ID: WP_230340173.1
Location: 1121842..1122060 (219 bp)
Type: Toxin
Protein ID: WP_230340183.1
Location: 1122373..1123263 (891 bp)
Type: Others
Protein ID: WP_230340184.1
Location: 1123282..1123977 (696 bp)
Type: Others
Protein ID: WP_230340185.1
Location: 1124125..1124670 (546 bp)
Type: Others
Protein ID: WP_230340186.1
Location: 1124618..1125604 (987 bp)
Type: Others
Protein ID: WP_230340187.1
Location: 1125582..1126016 (435 bp)
Type: Others
Protein ID: WP_230340188.1
Location: 1126029..1126283 (255 bp)
Type: Others
Protein ID: WP_230340189.1
Location: 1126329..1126553 (225 bp)
Type: Others
Protein ID: WP_230340190.1
Location: 1126566..1126895 (330 bp)
Type: Others
Protein ID: WP_230340191.1
Location: 1119178..1119786 (609 bp)
Type: Others
Protein ID: WP_230340180.1
Location: 1119971..1120165 (195 bp)
Type: Others
Protein ID: WP_230340181.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JQU52_RS05730 (JQU52_05760)1116849..1117532+684WP_230340178.1S24 family peptidase-
JQU52_RS05740 (JQU52_05770)1118647..1118817+171WP_230340179.1hypothetical protein-
JQU52_RS05745 (JQU52_05775)1119178..1119786-609WP_230340180.1hypothetical protein-
JQU52_RS05750 (JQU52_05780)1119971..1120165-195WP_230340181.1Cro/CI family transcriptional regulator-
JQU52_RS05755 (JQU52_05785)1120270..1120917+648WP_230340182.1S24 family peptidase-
JQU52_RS05760 (JQU52_05790)1121615..1121845+231WP_230340173.1antitoxin MazE family proteinAntitoxin
JQU52_RS05765 (JQU52_05795)1121842..1122060+219WP_230340183.1type II toxin-antitoxin system PemK/MazF family toxinToxin
JQU52_RS05775 (JQU52_05805)1122373..1123263+891WP_230340184.1hypothetical protein-
JQU52_RS05780 (JQU52_05810)1123282..1123977+696WP_230340185.1hypothetical protein-
JQU52_RS05785 (JQU52_05815)1124125..1124670+546WP_230340186.1TrbM/KikA/MpfK family conjugal transfer protein-
JQU52_RS05790 (JQU52_05820)1124618..1125604+987WP_230340187.1conjugal transfer protein TraL-
JQU52_RS05795 (JQU52_05825)1125582..1126016+435WP_230340188.1hypothetical protein-
JQU52_RS05800 (JQU52_05830)1126029..1126283+255WP_230340189.1toxin PIN-
JQU52_RS05805 (JQU52_05835)1126329..1126553+225WP_230340190.1hypothetical protein-
JQU52_RS05810 (JQU52_05840)1126566..1126895+330WP_230340191.1helix-turn-helix domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--1062617..112789365276


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-65)

Antitoxin

Antitoxin MazE-like

(7-68)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8039.40 Da        Isoelectric Point: 10.1054

>T191801 WP_230340183.1 NZ_CP069798:1121842-1122060 [Paralysiella testudinis]
MKRGDLITVAIQGDYGKLRPALVVQSDVFAGHTSICILPLTSDLHEAPLFRILLTPSSSNGLTKNHRLWWIR

Download         Length: 219 bp

>T191801 NZ_CP091913:3239825-3240109 [Nostoc sp. UHCC 0870]
GTGATTGTAAGTTTCAAATCTGAAGAGACAAAGCTCATTTTTGATGGCTTTATATCTGCTGAATACCCGCCAGATATTCA
AAAAGTTGCTTTACGAAAGCTGCTGATGCTGAATGCAGCAACATCAATTCAAGACTTGCGCGTTCCACCAGGTAATCGAT
TGGAAAAGCTAGTTGGGGACAGACAAGGACAATATAGCATTCGTATTAATGACCAGTGGCGAATCTGCTTTGTCTGGAGT
AATGAAAATAATGCGGATGAAGTTGAAATTGTAGACTACCACTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8492.66 Da        Isoelectric Point: 7.3207

>AT191801 WP_230340173.1 NZ_CP069798:1121615-1121845 [Paralysiella testudinis]
MMSNSASRVQQHRVRLRHAGLRPIQIWVPDTRRPGFAAEAHRQIALVAQGDRGDAQLAVMMDEALMNLADSGEWEA

Download         Length: 231 bp

>AT191801 NZ_CP091913:3240123-3240431 [Nostoc sp. UHCC 0870]
ATGAATAGTAATTGTTTACCAAATATCCATCCAGGCGAAATTCTGCAACTAGAATTTTTAGAGCCATTGAATATTACCCC
TTATCGGTTGAGTAAAGATATAGGTGTCACTCAGACAAGAATTGGCGAAATTTTATCAGGTAAACGCAGTATTACAGCAG
ATACAGCTTTGCGTTTATCGCGTTATTTTGGTAACAGTCCCCAGTTTTGGCTGAATTTGCAAATGCAATATGATTTACGT
CAAGCTTGGGTAGAAAAGGCAGATGTTTACAACCAGATTCCTGTGAATCCGTTTAATAGTGTAGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References