Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 3610923..3611541 | Replicon | chromosome |
Accession | NZ_CP069707 | ||
Organism | Escherichia coli strain E41 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | H5UYE2 |
Locus tag | JSQ86_RS17720 | Protein ID | WP_001291435.1 |
Coordinates | 3611323..3611541 (+) | Length | 73 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | S1PTH5 |
Locus tag | JSQ86_RS17715 | Protein ID | WP_000344800.1 |
Coordinates | 3610923..3611297 (+) | Length | 125 a.a. |
Genomic Context
Location: 3606012..3607205 (1194 bp)
Type: Others
Protein ID: WP_001295324.1
Type: Others
Protein ID: WP_001295324.1
Location: 3607228..3610377 (3150 bp)
Type: Others
Protein ID: WP_001132469.1
Type: Others
Protein ID: WP_001132469.1
Location: 3610923..3611297 (375 bp)
Type: Antitoxin
Protein ID: WP_000344800.1
Type: Antitoxin
Protein ID: WP_000344800.1
Location: 3611323..3611541 (219 bp)
Type: Toxin
Protein ID: WP_001291435.1
Type: Toxin
Protein ID: WP_001291435.1
Location: 3611713..3612264 (552 bp)
Type: Others
Protein ID: WP_000102564.1
Type: Others
Protein ID: WP_000102564.1
Location: 3612380..3612850 (471 bp)
Type: Others
Protein ID: WP_000136192.1
Type: Others
Protein ID: WP_000136192.1
Location: 3613014..3614564 (1551 bp)
Type: Others
Protein ID: WP_096976878.1
Type: Others
Protein ID: WP_096976878.1
Location: 3615338..3615649 (312 bp)
Type: Others
Protein ID: WP_000409911.1
Type: Others
Protein ID: WP_000409911.1
Location: 3614606..3614959 (354 bp)
Type: Others
Protein ID: WP_000878140.1
Type: Others
Protein ID: WP_000878140.1
Location: 3615680..3616252 (573 bp)
Type: Others
Protein ID: WP_000779831.1
Type: Others
Protein ID: WP_000779831.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JSQ86_RS17705 | 3606012..3607205 | + | 1194 | WP_001295324.1 | multidrug efflux RND transporter periplasmic adaptor subunit AcrA | - |
JSQ86_RS17710 | 3607228..3610377 | + | 3150 | WP_001132469.1 | multidrug efflux RND transporter permease subunit | - |
JSQ86_RS17715 | 3610923..3611297 | + | 375 | WP_000344800.1 | Hha toxicity modulator TomB | Antitoxin |
JSQ86_RS17720 | 3611323..3611541 | + | 219 | WP_001291435.1 | hemolysin expression modulator Hha | Toxin |
JSQ86_RS17725 | 3611713..3612264 | + | 552 | WP_000102564.1 | maltose O-acetyltransferase | - |
JSQ86_RS17730 | 3612380..3612850 | + | 471 | WP_000136192.1 | YlaC family protein | - |
JSQ86_RS17735 | 3613014..3614564 | + | 1551 | WP_096976878.1 | cyclic-guanylate-specific phosphodiesterase PdeB | - |
JSQ86_RS17740 | 3614606..3614959 | - | 354 | WP_000878140.1 | DUF1428 domain-containing protein | - |
JSQ86_RS17750 | 3615338..3615649 | + | 312 | WP_000409911.1 | MGMT family protein | - |
JSQ86_RS17755 | 3615680..3616252 | - | 573 | WP_000779831.1 | YbaY family lipoprotein | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 73 a.a. Molecular weight: 8628.00 Da Isoelectric Point: 8.9008
>T191695 WP_001291435.1 NZ_CP069707:3611323-3611541 [Escherichia coli]
MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
Download Length: 219 bp
>T191695 NZ_CP091884:424914-425189 [Enterococcus faecalis]
ATGCTTGAAATATTTTACACGAACCAATTCAAAAAAGACTTTAAGAAAGCAAAGAAACAAGGAAAGAATTTAGAGAAGTT
AAAAGAAGTATTAGTACTTTTACAAGAACAGCAAACATTGCCGCCAAAGTATAAAGACCACGCACTAACAGGAAATTATA
TAGGTACAAGAGAGTGCCATATTGAACCAGATTGGTTACTGATTTATAAAATTGACGGTGATAAATTGATCCTAACTTTA
GCTCGAATAGGCTCACATAGTGAATTATTTCGATGA
ATGCTTGAAATATTTTACACGAACCAATTCAAAAAAGACTTTAAGAAAGCAAAGAAACAAGGAAAGAATTTAGAGAAGTT
AAAAGAAGTATTAGTACTTTTACAAGAACAGCAAACATTGCCGCCAAAGTATAAAGACCACGCACTAACAGGAAATTATA
TAGGTACAAGAGAGTGCCATATTGAACCAGATTGGTTACTGATTTATAAAATTGACGGTGATAAATTGATCCTAACTTTA
GCTCGAATAGGCTCACATAGTGAATTATTTCGATGA
Antitoxin
Download Length: 125 a.a. Molecular weight: 14557.39 Da Isoelectric Point: 4.7395
>AT191695 WP_000344800.1 NZ_CP069707:3610923-3611297 [Escherichia coli]
MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYL
DDTFMLFSSYGINMQDLQKWRKSGNRLFRCFVNATKENPASLSC
MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYL
DDTFMLFSSYGINMQDLQKWRKSGNRLFRCFVNATKENPASLSC
Download Length: 375 bp
>AT191695 NZ_CP091884:424655-424921 [Enterococcus faecalis]
GTGGCTACTACAAAAAAGAAACCTATACATGTAAATGTTGATGAAAATTTAAAAGAAGAAGCAGAACAATTATTTGATGA
TTTAGGGTTAAATATGACAAGTGCAATTACGATTTTCTTAAAACAGTCTATTAATGAGCAAGCAATTCCTTTTATGATTA
ATAAGGGAAACAAAGAGACTCTACAAGCATTAAAAGACATTAAAGAAGGAAATGTTCATGGTGGATTTTCTTCCGTGGAG
GATTTAATGGAGGATTTAAATGCTTGA
GTGGCTACTACAAAAAAGAAACCTATACATGTAAATGTTGATGAAAATTTAAAAGAAGAAGCAGAACAATTATTTGATGA
TTTAGGGTTAAATATGACAAGTGCAATTACGATTTTCTTAAAACAGTCTATTAATGAGCAAGCAATTCCTTTTATGATTA
ATAAGGGAAACAAAGAGACTCTACAAGCATTAAAAGACATTAAAGAAGGAAATGTTCATGGTGGATTTTCTTCCGTGGAG
GATTTAATGGAGGATTTAAATGCTTGA