Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 732999..733677 Replicon chromosome
Accession NZ_CP069605
Organism Dickeya dianthicola strain 16JP03

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JRZ92_RS03395 Protein ID WP_024104636.1
Coordinates 733246..733677 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A3A4CJ89
Locus tag JRZ92_RS03390 Protein ID WP_024104635.1
Coordinates 732999..733265 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JRZ92_RS03375 (JRZ92_03385) 730094..730702 - 609 WP_024104632.1 HD domain-containing protein -
JRZ92_RS03380 (JRZ92_03390) 730964..731614 + 651 WP_024104633.1 hemolysin III family protein -
JRZ92_RS03385 (JRZ92_03395) 731705..732685 - 981 WP_024104634.1 tRNA-modifying protein YgfZ -
JRZ92_RS03390 (JRZ92_03400) 732999..733265 + 267 WP_024104635.1 FAD assembly factor SdhE Antitoxin
JRZ92_RS03395 (JRZ92_03405) 733246..733677 + 432 WP_024104636.1 protein YgfX Toxin
JRZ92_RS03400 (JRZ92_03410) 733772..734290 - 519 WP_024104637.1 flavodoxin FldB -
JRZ92_RS03405 (JRZ92_03415) 734419..735744 - 1326 WP_024104638.1 MFS transporter -
JRZ92_RS03410 (JRZ92_03420) 736007..736906 + 900 WP_024104639.1 site-specific tyrosine recombinase XerD -
JRZ92_RS03415 (JRZ92_03425) 736996..737712 + 717 WP_024104640.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16839.52 Da        Isoelectric Point: 11.7737

>T191258 WP_024104636.1 NZ_CP069605:733246-733677 [Dickeya dianthicola]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWSDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIVRRPWVMRNGVLLSLRATNGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH

Download         Length: 432 bp

>T191258 NZ_CP091665:223063-223170 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10471.02 Da        Isoelectric Point: 6.0666

>AT191258 WP_024104635.1 NZ_CP069605:732999-733265 [Dickeya dianthicola]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKLHFIRLLQCDDPDLFNWLMNHGEPVDPALKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT191258 NZ_CP091665:c223014-222951 [Escherichia coli]
GTCTAGATGCAAGAATGGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3A4CJ89

References