191256

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2368927..2369837 Replicon chromosome
Accession NZ_CP069604
Organism Dickeya dianthicola strain 16JP05

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag JRZ84_RS10895 Protein ID WP_024105930.1
Coordinates 2369367..2369837 (+) Length 157 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A3A4C852
Locus tag JRZ84_RS10890 Protein ID WP_024105929.1
Coordinates 2368927..2369370 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JRZ84_RS10865 (JRZ84_10860) 2363985..2364656 + 672 WP_024105924.1 dethiobiotin synthase -
JRZ84_RS10870 (JRZ84_10865) 2364930..2365286 - 357 WP_024105925.1 DUF1283 family protein -
JRZ84_RS10875 (JRZ84_10870) 2365492..2366241 - 750 WP_024105926.1 bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG -
JRZ84_RS10880 (JRZ84_10875) 2366545..2367771 - 1227 WP_024105927.1 glycosyl transferase -
JRZ84_RS10885 (JRZ84_10880) 2367790..2368617 - 828 WP_024105928.1 mannosyl-3-phosphoglycerate phosphatase-related protein -
JRZ84_RS10890 (JRZ84_10885) 2368927..2369370 + 444 WP_024105929.1 DUF2384 domain-containing protein Antitoxin
JRZ84_RS10895 (JRZ84_10890) 2369367..2369837 + 471 WP_024105930.1 RES family NAD+ phosphorylase Toxin
JRZ84_RS10900 (JRZ84_10895) 2369843..2370130 + 288 WP_024105931.1 hypothetical protein -
JRZ84_RS10905 (JRZ84_10900) 2370513..2371517 - 1005 WP_103415876.1 acyltransferase family protein -
JRZ84_RS10910 (JRZ84_10905) 2372209..2373170 + 962 Protein_2147 dicarboxylate transporter/tellurite-resistance protein TehA -
JRZ84_RS10915 (JRZ84_10910) 2373477..2374169 + 693 WP_223303748.1 expansin EXLX1 family cellulose-binding protein -
JRZ84_RS10920 (JRZ84_10915) 2374463..2374780 - 318 WP_223303749.1 TetR/AcrR family transcriptional regulator C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre

(16-147)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17578.95 Da        Isoelectric Point: 4.7269

>T191256 WP_024105930.1 NZ_CP069604:2369367-2369837 [Dickeya dianthicola]
MILYRLTKTKYLSTVWTGYGAKEAGGRWNSVGVSMVYVSETASLTMLETLVHLHAAHILDYYTLLRIDVPDDHIQSVNMN
DLPENWAEEDAPPELAAYGDAWCFTKSSIALRVPSTLSPVEFNYLLNPEHPDFSSIIQNADTIPFQFDSRLKPAIK

Download         Length: 471 bp

>T191256 NZ_CP091665:222096-222203 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGCATGAT
CGTGAACTGGCTGAATAAGCGGAAGTAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16506.81 Da        Isoelectric Point: 9.6195

>AT191256 WP_024105929.1 NZ_CP069604:2368927-2369370 [Dickeya dianthicola]
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLDGTVANVIIDWAKITQNDLRKMSGIPSTTFSRSRKARFTADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKVPAELMASETGAYEVMKLITRLEHGAYS

Download         Length: 444 bp

>AT191256 NZ_CP091665:c222047-221984 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3A4C852

References