Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 2368927..2369837 | Replicon | chromosome |
| Accession | NZ_CP069603 | ||
| Organism | Dickeya dianthicola strain 16LI01 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | JRZ91_RS10905 | Protein ID | WP_024105930.1 |
| Coordinates | 2369367..2369837 (+) | Length | 157 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A3A4C852 |
| Locus tag | JRZ91_RS10900 | Protein ID | WP_024105929.1 |
| Coordinates | 2368927..2369370 (+) | Length | 148 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JRZ91_RS10875 (JRZ91_10875) | 2363985..2364656 | + | 672 | WP_024105924.1 | dethiobiotin synthase | - |
| JRZ91_RS10880 (JRZ91_10880) | 2364930..2365286 | - | 357 | WP_024105925.1 | DUF1283 family protein | - |
| JRZ91_RS10885 (JRZ91_10885) | 2365492..2366241 | - | 750 | WP_024105926.1 | bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG | - |
| JRZ91_RS10890 (JRZ91_10890) | 2366545..2367771 | - | 1227 | WP_024105927.1 | glycosyl transferase | - |
| JRZ91_RS10895 (JRZ91_10895) | 2367790..2368617 | - | 828 | WP_024105928.1 | mannosyl-3-phosphoglycerate phosphatase-related protein | - |
| JRZ91_RS10900 (JRZ91_10900) | 2368927..2369370 | + | 444 | WP_024105929.1 | DUF2384 domain-containing protein | Antitoxin |
| JRZ91_RS10905 (JRZ91_10905) | 2369367..2369837 | + | 471 | WP_024105930.1 | RES family NAD+ phosphorylase | Toxin |
| JRZ91_RS10910 (JRZ91_10910) | 2369843..2370130 | + | 288 | WP_024105931.1 | hypothetical protein | - |
| JRZ91_RS10915 (JRZ91_10915) | 2370513..2371517 | - | 1005 | WP_103415876.1 | acyltransferase family protein | - |
| JRZ91_RS10920 (JRZ91_10920) | 2372209..2373170 | + | 962 | Protein_2149 | dicarboxylate transporter/tellurite-resistance protein TehA | - |
| JRZ91_RS10925 (JRZ91_10925) | 2373477..2374169 | + | 693 | WP_223303748.1 | expansin EXLX1 family cellulose-binding protein | - |
| JRZ91_RS10930 (JRZ91_10930) | 2374463..2374780 | - | 318 | WP_223303749.1 | TetR/AcrR family transcriptional regulator C-terminal domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 157 a.a. Molecular weight: 17578.95 Da Isoelectric Point: 4.7269
>T191238 WP_024105930.1 NZ_CP069603:2369367-2369837 [Dickeya dianthicola]
MILYRLTKTKYLSTVWTGYGAKEAGGRWNSVGVSMVYVSETASLTMLETLVHLHAAHILDYYTLLRIDVPDDHIQSVNMN
DLPENWAEEDAPPELAAYGDAWCFTKSSIALRVPSTLSPVEFNYLLNPEHPDFSSIIQNADTIPFQFDSRLKPAIK
MILYRLTKTKYLSTVWTGYGAKEAGGRWNSVGVSMVYVSETASLTMLETLVHLHAAHILDYYTLLRIDVPDDHIQSVNMN
DLPENWAEEDAPPELAAYGDAWCFTKSSIALRVPSTLSPVEFNYLLNPEHPDFSSIIQNADTIPFQFDSRLKPAIK
Download Length: 471 bp
>T191238 NZ_CP091664:1233085-1233396 [Escherichia coli]
ATGCACATCATTTCGAAAGCGCCATTTGAAGAGTGTGCGCGCAAATATCCTAACGACGCTCTGGCTCTACACTCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCTAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA
ATGCACATCATTTCGAAAGCGCCATTTGAAGAGTGTGCGCGCAAATATCCTAACGACGCTCTGGCTCTACACTCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCTAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA
Antitoxin
Download Length: 148 a.a. Molecular weight: 16506.81 Da Isoelectric Point: 9.6195
>AT191238 WP_024105929.1 NZ_CP069603:2368927-2369370 [Dickeya dianthicola]
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLDGTVANVIIDWAKITQNDLRKMSGIPSTTFSRSRKARFTADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKVPAELMASETGAYEVMKLITRLEHGAYS
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLDGTVANVIIDWAKITQNDLRKMSGIPSTTFSRSRKARFTADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKVPAELMASETGAYEVMKLITRLEHGAYS
Download Length: 444 bp
>AT191238 NZ_CP091664:1233393-1233812 [Escherichia coli]
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAATATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCAGCAATGCCGGTT
GGCGTGGCCTTACTTCGTACGCTGATTGATCAACATAATTTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
TCTGGTCAGTCAGATTTTGTCTGGGCAACGATCCCTGACGATATCCCATATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAATATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCAGCAATGCCGGTT
GGCGTGGCCTTACTTCGTACGCTGATTGATCAACATAATTTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
TCTGGTCAGTCAGATTTTGTCTGGGCAACGATCCCTGACGATATCCCATATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|