Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 1258942..1259567 | Replicon | chromosome |
Accession | NZ_CP069603 | ||
Organism | Dickeya dianthicola strain 16LI01 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | E0SD87 |
Locus tag | JRZ91_RS05905 | Protein ID | WP_009114000.1 |
Coordinates | 1258942..1259145 (-) | Length | 68 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | A0A3A4CQB3 |
Locus tag | JRZ91_RS05910 | Protein ID | WP_024104994.1 |
Coordinates | 1259199..1259567 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JRZ91_RS05875 (JRZ91_05875) | 1254415..1254753 | + | 339 | WP_024104989.1 | P-II family nitrogen regulator | - |
JRZ91_RS05880 (JRZ91_05880) | 1254796..1256088 | + | 1293 | WP_024104990.1 | ammonium transporter AmtB | - |
JRZ91_RS05885 (JRZ91_05885) | 1256198..1257061 | - | 864 | WP_024108455.1 | acyl-CoA thioesterase II | - |
JRZ91_RS05890 (JRZ91_05890) | 1257333..1257890 | + | 558 | WP_024108456.1 | YbaY family lipoprotein | - |
JRZ91_RS05895 (JRZ91_05895) | 1257919..1258248 | - | 330 | WP_024104993.1 | MGMT family protein | - |
JRZ91_RS05905 (JRZ91_05905) | 1258942..1259145 | - | 204 | WP_009114000.1 | HHA domain-containing protein | Toxin |
JRZ91_RS05910 (JRZ91_05910) | 1259199..1259567 | - | 369 | WP_024104994.1 | Hha toxicity modulator TomB | Antitoxin |
JRZ91_RS05915 (JRZ91_05915) | 1260076..1260219 | - | 144 | WP_013316871.1 | type B 50S ribosomal protein L36 | - |
JRZ91_RS05920 (JRZ91_05920) | 1260235..1260486 | - | 252 | WP_024108457.1 | type B 50S ribosomal protein L31 | - |
JRZ91_RS05925 (JRZ91_05925) | 1260657..1263806 | - | 3150 | WP_024108458.1 | efflux RND transporter permease subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 68 a.a. Molecular weight: 8133.51 Da Isoelectric Point: 8.8500
>T191225 WP_009114000.1 NZ_CP069603:c1259145-1258942 [Dickeya dianthicola]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWKYVR
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWKYVR
Download Length: 204 bp
>T191225 NZ_CP091662:c3927762-3927475 [Escherichia coli]
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA
ATGCCAATGGAGTTTGAATGGGATGAAAACAAGGCCAAAAGTAATCGGGTGAAACATGGCATCCGCTTTGAAGATGCGGT
GTTATTGTTTGATGATCCACAACATTTGTCACAGCAAGAACGCATAGAAAACGGTGAGTATCGCTGGCAGACAATCGGCC
TGGTTTACGGCATCGTGGTTATTCTGGTTGCGCATACCATCCGTTTCGAAAGCGGAAATGAAATTATTCGAATCATCAGT
GCACGAAAAGCAGATCGTAAAGAGAGGAATCGCTATGAGCATGGTTAA
Antitoxin
Download Length: 123 a.a. Molecular weight: 14242.11 Da Isoelectric Point: 5.1811
>AT191225 WP_024104994.1 NZ_CP069603:c1259567-1259199 [Dickeya dianthicola]
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSRSWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDAELQKWRKSKSQLFRMFSEKSICTVVKT
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSRSWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDAELQKWRKSKSQLFRMFSEKSICTVVKT
Download Length: 369 bp
>AT191225 NZ_CP091662:c3927488-3927186 [Escherichia coli]
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGGCGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA
ATGAGCATGGTTAAACATAAACGAGGGACCTCCTCTACACTCGATGTGCAGCATGAGGCCGAACTGAAGGCGCTGGCGAA
TAAATCCGACGAAGATATTGATTACAGTGATATCCCACCTTCCAGCGATGAGCAATGGTCTAACGCCGAACGCGGTAAGT
TTTATCGGCCATTGAAAACTCAGGCTTCGGTGCGTATTGATGCTGATGTGATGGAATGGTTGAAGCGACCAGGTAAAGGC
TATCAAACTCGCCTGAACGCAATTTTACGTGAAGCGATGCTGCGCGATCAGAACAAAAAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1X3RNQ0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A3A4CQB3 |