Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 732999..733677 | Replicon | chromosome |
Accession | NZ_CP069601 | ||
Organism | Dickeya dianthicola strain 16LI04 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | - |
Locus tag | JRZ89_RS03400 | Protein ID | WP_024104636.1 |
Coordinates | 733246..733677 (+) | Length | 144 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | A0A3A4CJ89 |
Locus tag | JRZ89_RS03395 | Protein ID | WP_024104635.1 |
Coordinates | 732999..733265 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JRZ89_RS03380 (JRZ89_03370) | 730094..730702 | - | 609 | WP_024104632.1 | HD domain-containing protein | - |
JRZ89_RS03385 (JRZ89_03375) | 730964..731614 | + | 651 | WP_024104633.1 | hemolysin III family protein | - |
JRZ89_RS03390 (JRZ89_03380) | 731705..732685 | - | 981 | WP_024104634.1 | tRNA-modifying protein YgfZ | - |
JRZ89_RS03395 (JRZ89_03385) | 732999..733265 | + | 267 | WP_024104635.1 | FAD assembly factor SdhE | Antitoxin |
JRZ89_RS03400 (JRZ89_03390) | 733246..733677 | + | 432 | WP_024104636.1 | protein YgfX | Toxin |
JRZ89_RS03405 (JRZ89_03395) | 733772..734290 | - | 519 | WP_024104637.1 | flavodoxin FldB | - |
JRZ89_RS03410 (JRZ89_03400) | 734419..735744 | - | 1326 | WP_024104638.1 | MFS transporter | - |
JRZ89_RS03415 (JRZ89_03405) | 736007..736906 | + | 900 | WP_024104639.1 | site-specific tyrosine recombinase XerD | - |
JRZ89_RS03420 (JRZ89_03410) | 736996..737712 | + | 717 | WP_024104640.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 144 a.a. Molecular weight: 16839.52 Da Isoelectric Point: 11.7737
>T191186 WP_024104636.1 NZ_CP069601:733246-733677 [Dickeya dianthicola]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWSDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIVRRPWVMRNGVLLSLRATNGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWSDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIVRRPWVMRNGVLLSLRATNGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH
Download Length: 432 bp
>T191186 NZ_CP091659:c1334378-1334064 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10471.02 Da Isoelectric Point: 6.0666
>AT191186 WP_024104635.1 NZ_CP069601:732999-733265 [Dickeya dianthicola]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKLHFIRLLQCDDPDLFNWLMNHGEPVDPALKRMVSLIQTRN
KDRGPVAM
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKLHFIRLLQCDDPDLFNWLMNHGEPVDPALKRMVSLIQTRN
KDRGPVAM
Download Length: 267 bp
>AT191186 NZ_CP091659:c1334067-1333651 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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