191186

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 732999..733677 Replicon chromosome
Accession NZ_CP069601
Organism Dickeya dianthicola strain 16LI04

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JRZ89_RS03400 Protein ID WP_024104636.1
Coordinates 733246..733677 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A3A4CJ89
Locus tag JRZ89_RS03395 Protein ID WP_024104635.1
Coordinates 732999..733265 (+) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JRZ89_RS03380 (JRZ89_03370) 730094..730702 - 609 WP_024104632.1 HD domain-containing protein -
JRZ89_RS03385 (JRZ89_03375) 730964..731614 + 651 WP_024104633.1 hemolysin III family protein -
JRZ89_RS03390 (JRZ89_03380) 731705..732685 - 981 WP_024104634.1 tRNA-modifying protein YgfZ -
JRZ89_RS03395 (JRZ89_03385) 732999..733265 + 267 WP_024104635.1 FAD assembly factor SdhE Antitoxin
JRZ89_RS03400 (JRZ89_03390) 733246..733677 + 432 WP_024104636.1 protein YgfX Toxin
JRZ89_RS03405 (JRZ89_03395) 733772..734290 - 519 WP_024104637.1 flavodoxin FldB -
JRZ89_RS03410 (JRZ89_03400) 734419..735744 - 1326 WP_024104638.1 MFS transporter -
JRZ89_RS03415 (JRZ89_03405) 736007..736906 + 900 WP_024104639.1 site-specific tyrosine recombinase XerD -
JRZ89_RS03420 (JRZ89_03410) 736996..737712 + 717 WP_024104640.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-132)

Antitoxin

(8-79)


Sequences


Toxin        


Download         Length: 144 a.a.        Molecular weight: 16839.52 Da        Isoelectric Point: 11.7737

>T191186 WP_024104636.1 NZ_CP069601:733246-733677 [Dickeya dianthicola]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWSDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIVRRPWVMRNGVLLSLRATNGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH

Download         Length: 432 bp

>T191186 NZ_CP091659:c1334378-1334064 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10471.02 Da        Isoelectric Point: 6.0666

>AT191186 WP_024104635.1 NZ_CP069601:732999-733265 [Dickeya dianthicola]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKLHFIRLLQCDDPDLFNWLMNHGEPVDPALKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT191186 NZ_CP091659:c1334067-1333651 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A3A4CJ89

References