Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 684646..685242 Replicon chromosome
Accession NZ_CP069594
Organism Pseudomonas sp. Y39-6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JN756_RS02955 Protein ID WP_108526130.1
Coordinates 684940..685242 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1D3JR09
Locus tag JN756_RS02950 Protein ID WP_017849687.1
Coordinates 684646..684936 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN756_RS02930 (JN756_02905) 681012..683087 - 2076 WP_026140374.1 TonB-dependent copper receptor -
JN756_RS02935 (JN756_02910) 683181..683612 - 432 WP_102618699.1 DUF2946 domain-containing protein -
JN756_RS02940 (JN756_02915) 683624..684106 - 483 WP_057006060.1 copper chaperone PCu(A)C -
JN756_RS02945 (JN756_02920) 684154..684549 - 396 WP_046485671.1 DUF2946 domain-containing protein -
JN756_RS02950 (JN756_02925) 684646..684936 - 291 WP_017849687.1 putative addiction module antidote protein Antitoxin
JN756_RS02955 (JN756_02930) 684940..685242 - 303 WP_108526130.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JN756_RS02960 (JN756_02935) 685599..686318 - 720 WP_128192597.1 cobalt-precorrin-6A reductase -
JN756_RS02965 (JN756_02940) 686315..687520 - 1206 WP_201021765.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
JN756_RS02970 (JN756_02945) 687559..688911 + 1353 WP_046384856.1 precorrin-3B synthase -
JN756_RS02975 (JN756_02950) 688904..689530 + 627 WP_046384855.1 precorrin-8X methylmutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11492.38 Da        Isoelectric Point: 8.5041

>T191074 WP_108526130.1 NZ_CP069594:c685242-684940 [Pseudomonas sp. Y39-6]
MIEFEESVEFVKWLEAMRDPLAKVRIVTRLRMAQAGNFGDCEAVGEGVCEMRIHQGPGYRVYFTLRDKVVYLLLMGGDKS
TQSRDIQRAIHMAKNLGRKE

Download         Length: 303 bp

>T191074 NZ_CP091634:2004069-2004172 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10437.00 Da        Isoelectric Point: 5.8124

>AT191074 WP_017849687.1 NZ_CP069594:c684936-684646 [Pseudomonas sp. Y39-6]
MSESFTRFDAAKYLKTPFEMAAYLDACFEEDAGDGLLIRTALNDIARAQGMTQVARDAGLGRESLYKALSSTGNPEFATI
MKVMRALGLKLHATAL

Download         Length: 291 bp

>AT191074 NZ_CP091634:c2004174-2004031 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1D3JR09

References