Detailed information of TA system TA191073

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/-
• Location: 369525..370014
• Replicon: chromosome
• Accession: NZ_CP069594
• Organism: Pseudomonas sp. Y39-6

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1D3JQH6
• Locus tag: JN756_RS01580
• Protein ID: WP_032805156.1
• Coordinates: 369703..370014 (+)
• Length: 104 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JN756_RS01575
• Protein ID: WP_081610227.1
• Coordinates: 369525..369716 (+)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JN756_RS01555 (JN756_01535)	365081..365854	-	774	WP_017849951.1	ABC transporter ATP-binding protein	-
JN756_RS01560 (JN756_01540)	366410..367801	+	1392	WP_017849950.1	GABA permease	-
JN756_RS01565 (JN756_01545)	367881..368294	-	414	WP_201021732.1	hypothetical protein	-
JN756_RS01570 (JN756_01550)	368364..369311	-	948	WP_108526630.1	alpha/beta fold hydrolase	-
JN756_RS01575 (JN756_01555)	369525..369716	+	192	WP_081610227.1	antitoxin	Antitoxin
JN756_RS01580 (JN756_01560)	369703..370014	+	312	WP_032805156.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JN756_RS01585 (JN756_01565)	370056..371030	+	975	WP_079442658.1	arsenic resistance protein	-
JN756_RS01590 (JN756_01570)	371109..372716	+	1608	WP_126585334.1	glycosyltransferase family 39 protein	-
JN756_RS01600 (JN756_01580)	373039..373311	-	273	WP_017849944.1	oxidative damage protection protein	-
JN756_RS01605 (JN756_01585)	373308..374375	-	1068	WP_201021733.1	A/G-specific adenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-89)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 104 a.a.
• Molecular weight: 11782.70 Da
• Isoelectric Point: 7.1408

>T191073 WP_032805156.1 NZ_CP069594:369703-370014 [Pseudomonas sp. Y39-6]
VLLVKWRPEAIVALIEIIDYIEQYNPVAAVSLHQTIVVAAEGLSLMPYGFKHGRLSGTREMVVHPNYLVVYRVTEHVEIV
MVLHTRQEYPRDVIGPHHSTSRQ

Nucleotide

• Length: 312 bp

>T191073 NZ_CP091634:c1009332-1008805 [Salmonella enterica]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGAAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGGGATACGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGTGGCGTAGCCCTGCTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTACTG
TCGTTTAAAACGCTTTATGCGGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7300.17 Da
• Isoelectric Point: 5.8317

>AT191073 WP_081610227.1 NZ_CP069594:369525-369716 [Pseudomonas sp. Y39-6]
MSIPRSPIVSEFETEEQAASYDRWFRAKVQASIDDPRPSIPHDQAMAEVEKVLEERRKARASR

Nucleotide

• Length: 192 bp

>AT191073 NZ_CP091634:c1009619-1009329 [Salmonella enterica]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTGCGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGCGATACTCAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCCGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Structures

Toxin

• AlphaFold DB: A0A1D3JQH6