Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 498048..498701 Replicon chromosome
Accession NZ_CP069586
Organism Acinetobacter pittii strain FDAARGOS_1216

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag I6J46_RS02265 Protein ID WP_204085520.1
Coordinates 498048..498437 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag I6J46_RS02270 Protein ID WP_141314856.1
Coordinates 498444..498701 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6J46_RS02250 493154..495349 - 2196 WP_017400431.1 TRAP transporter large permease subunit -
I6J46_RS02255 495529..496104 - 576 WP_005078319.1 rhombosortase -
I6J46_RS02260 496189..497277 - 1089 WP_014207738.1 hypothetical protein -
I6J46_RS02265 498048..498437 - 390 WP_204085520.1 hypothetical protein Toxin
I6J46_RS02270 498444..498701 - 258 WP_141314856.1 succinate dehydrogenase assembly factor 2 Antitoxin
I6J46_RS02275 498890..500062 + 1173 WP_068929632.1 acyl-CoA dehydrogenase family protein -
I6J46_RS02280 500113..501603 - 1491 WP_202724341.1 NAD(P)/FAD-dependent oxidoreductase -
I6J46_RS02285 501785..502162 - 378 WP_002049717.1 50S ribosomal protein L17 -
I6J46_RS02290 502181..503188 - 1008 WP_002116730.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15547.69 Da        Isoelectric Point: 8.7390

>T191033 WP_204085520.1 NZ_CP069586:c498437-498048 [Acinetobacter pittii]
MIKELNFELKYSRVSVIFQLFVGLGLAILLYQLLTPIWWLCVVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YRAEITKIIDYQLFVVIYLEETPTNIAIVWFDQLPIQQWKRLKVLEKIY

Download         Length: 390 bp

>T191033 NZ_CP091622:3319448-3319666 [Salmonella enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10323.78 Da        Isoelectric Point: 4.4809

>AT191033 WP_141314856.1 NZ_CP069586:c498701-498444 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPVEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Download         Length: 258 bp

>AT191033 NZ_CP091622:3319046-3319420 [Salmonella enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References