Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2527117..2527388 Replicon chromosome
Accession NZ_CP069542
Organism Escherichia coli strain FDAARGOS_1248

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2527247..2527350 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2527117..2527388 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6J78_RS11875 2523672..2524334 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6J78_RS11880 2524358..2525014 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
I6J78_RS11885 2525116..2525346 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6J78_RS11890 2525485..2525859 + 375 WP_000168738.1 CopC domain-containing protein YobA -
I6J78_RS11895 2525863..2526735 + 873 WP_000879286.1 copper homeostasis membrane protein CopD -
I6J78_RS11900 2526748..2527089 + 342 WP_000976472.1 YebY family protein -
- 2527117..2527388 - 272 - - Antitoxin
- 2527247..2527350 + 104 - - Toxin
I6J78_RS11905 2527485..2528141 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
I6J78_RS11910 2528142..2528333 - 192 WP_001313035.1 YebW family protein -
I6J78_RS11915 2528438..2528674 - 237 WP_001295499.1 DUF1480 family protein -
I6J78_RS11920 2528792..2530231 - 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T190846 NZ_CP069542:2527247-2527350 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT190846 NZ_CP069542:c2527388-2527117 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References