Detailed information of TA system TA190835

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 83017..83670
• Replicon: chromosome
• Accession: NZ_CP069537
• Organism: Acinetobacter pittii strain FDAARGOS_1214

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: I6J44_RS00450
• Protein ID: WP_016802636.1
• Coordinates: 83017..83406 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A009HHW9
• Locus tag: I6J44_RS00455
• Protein ID: WP_002117064.1
• Coordinates: 83413..83670 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6J44_RS00435	78108..80318	-	2211	WP_002116854.1	TRAP transporter large permease subunit	-
I6J44_RS00440	80498..81073	-	576	WP_005078319.1	rhombosortase	-
I6J44_RS00445	81158..82246	-	1089	WP_002116869.1	hypothetical protein	-
I6J44_RS00450	83017..83406	-	390	WP_016802636.1	hypothetical protein	Toxin
I6J44_RS00455	83413..83670	-	258	WP_002117064.1	succinate dehydrogenase assembly factor 2	Antitoxin
I6J44_RS00460	83859..85031	+	1173	WP_002116790.1	acyl-CoA dehydrogenase family protein	-
I6J44_RS00465	85082..86572	-	1491	WP_002116796.1	NAD(P)/FAD-dependent oxidoreductase	-
I6J44_RS00470	86754..87131	-	378	WP_002049717.1	50S ribosomal protein L17	-
I6J44_RS00475	87150..88157	-	1008	WP_002116730.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15475.66 Da
• Isoelectric Point: 7.9230

>T190835 WP_016802636.1 NZ_CP069537:c83406-83017 [Acinetobacter pittii]
MIKELNFELKYSLVSVIFQLFVGLGLAILLYQLLTPIWWLCAVILLFIGFIFFLKQAQISQIEYLDQKLWSVAYFSKKEI
YRAEITKIIDYQLFVVIYLEETPTIIAIVWFDQLPIQQWKRLKVLEKLY

Nucleotide

• Length: 390 bp

>T190835 NZ_CP091558:c4460838-4460470 [Salmonella enterica]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTACCGGGTACTCAAGCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGTACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGCCGTTCGCTTACGTGCCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10295.73 Da
• Isoelectric Point: 4.4809

>AT190835 WP_002117064.1 NZ_CP069537:c83670-83413 [Acinetobacter pittii]
MSDEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVDQEDPDLLDWFMEVSEPPRTELREFIYKLK
QYVHG

Nucleotide

• Length: 258 bp

>AT190835 NZ_CP091558:c4461056-4460835 [Salmonella enterica]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGTGCGGTGACGGGGGGGCCTGTTAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGGAGCTGGCGGATAAATGA

Structures

Antitoxin

• AlphaFold DB: A0A009HHW9