Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-DinJ
Location 7747..8293 Replicon plasmid unnamed
Accession NZ_CP069521
Organism Enterocloster bolteae strain FDAARGOS_1231

Toxin (Protein)


Gene name relE Uniprot ID A8S0R9
Locus tag I6J61_RS30300 Protein ID WP_007038024.1
Coordinates 8015..8293 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A414AJ69
Locus tag I6J61_RS30295 Protein ID WP_007038025.1
Coordinates 7747..8022 (+) Length 92 a.a.

Genomic Context

I6J61_RS30295I6J61_RS30300I6J61_RS30310I6J61_RS30260I6J61_RS30265I6J61_RS30270I6J61_RS30275I6J61_RS30280I6J61_RS30285I6J61_RS30290I6J61_RS30305I6J61_RS30315
Location: 7747..8022 (276 bp)
Type: Antitoxin
Protein ID: WP_007038025.1
Location: 8015..8293 (279 bp)
Type: Toxin
Protein ID: WP_007038024.1
Location: 8915..9214 (300 bp)
Type: Others
Protein ID: WP_039897589.1
Location: 3792..4589 (798 bp)
Type: Others
Protein ID: WP_007038033.1
Location: 4701..4958 (258 bp)
Type: Others
Protein ID: WP_007038032.1
Location: 5015..5359 (345 bp)
Type: Others
Protein ID: WP_007038031.1
Location: 5390..5641 (252 bp)
Type: Others
Protein ID: WP_007038030.1
Location: 6046..6789 (744 bp)
Type: Others
Protein ID: WP_039897592.1
Location: 6863..7075 (213 bp)
Type: Others
Protein ID: WP_007038027.1
Location: 7059..7316 (258 bp)
Type: Others
Protein ID: WP_007038026.1
Location: 8443..8778 (336 bp)
Type: Others
Protein ID: WP_039897591.1
Location: 10449..11285 (837 bp)
Type: Others
Protein ID: WP_007038019.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I6J61_RS302603792..4589-798WP_007038033.1hypothetical protein-
I6J61_RS302654701..4958-258WP_007038032.1hypothetical protein-
I6J61_RS302705015..5359-345WP_007038031.1hypothetical protein-
I6J61_RS302755390..5641-252WP_007038030.1hypothetical protein-
I6J61_RS302806046..6789-744WP_039897592.1AAA family ATPase-
I6J61_RS302856863..7075-213WP_007038027.1hypothetical protein-
I6J61_RS302907059..7316-258WP_007038026.1hypothetical protein-
I6J61_RS302957747..8022+276WP_007038025.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
I6J61_RS303008015..8293+279WP_007038024.1type II toxin-antitoxin system YafQ family toxinToxin
I6J61_RS303058443..8778-336WP_039897591.1hypothetical protein-
I6J61_RS303108915..9214+300WP_039897589.1helix-turn-helix domain-containing protein-
I6J61_RS3031510449..11285-837WP_007038019.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..4377243772


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-85)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10942.65 Da        Isoelectric Point: 8.4737

>T190760 WP_007038024.1 NZ_CP069521:8015-8293 [Enterocloster bolteae]
MLKIEYQGQFKKDYKLALKRGCNPELLTEVISMLANEQELPEKYRDHNLMNSRSYKNARECHIQPDWLLIYQTNKDILTL
KLLRTGSHSDLF

Download         Length: 279 bp

>T190760 NZ_CP091544:207582-208067 [Salmonella enterica]
GTGGGACGTGTAACAGCACCAGAACCTTTGTCCGCTTTTCATCAGGTAGCTGAGTTCGTCAGCGGTGAAGCTGTGCTCGA
TGACTGGTTGAAGCAAAAGGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACATTTGTGGTGTGCAAGAAAGACACGA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGTAGCGTCAACCATACAGAAGCGACAGGCAACCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATTATACTTGCCCGTCTTGCTGTCGATCTCTCATTCCATGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATCATGGTTCATGCACTTACCG
AAGAAGCCAAAAATTTCTACATTCACCATGGTTTCAAATCATCACAAACTCAGCAGCGAACATTGTTCCTTAGGCTCCCT
CAATAG

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10209.60 Da        Isoelectric Point: 4.5388

>AT190760 WP_007038025.1 NZ_CP069521:7747-8022 [Enterocloster bolteae]
MSEKNTSMNIRMNKDVKLQAQKVFSDLGIDLTTAVNVFLRQSIRYQGFPFDVTLRQEPNATTMAAIENADKGIDMHGPFE
SVEALMEDLNA

Download         Length: 276 bp

>AT190760 NZ_CP091544:207307-207594 [Salmonella enterica]
ATGCTATACAAGGGGTGTCTCATGAAATCAGATGTTCAACTTAACCTTAGAGCTAAGGAATCGCAGCGGGCGCTCATTGA
TGCAGCTGCGGAAATCCTTCACAAGTCACGTACAGATTTCATTCTGGAAACGGCCTGCCAGGCTGCCGAGAAAGTGATCC
TTGACCGCCGTGTATTTAACTTTAACGATGAGCAATATGAGGAGTTCATCAATCTGCTTGATGCACCGGTCGCAGATGAT
CCCGTTATCGAAAAACTGCTGGCAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA8S0R9

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A414AJ69

References