Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014751..2015022 Replicon chromosome
Accession NZ_CP069501
Organism Escherichia coli strain FDAARGOS_1268

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014882..2014984 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014751..2015022 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6J98_RS09595 2011306..2011968 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6J98_RS09600 2011992..2012648 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein -
I6J98_RS09605 2012750..2012980 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6J98_RS09610 2013119..2013493 + 375 WP_000168737.1 CopC domain-containing protein YobA -
I6J98_RS09615 2013497..2014369 + 873 WP_000879323.1 copper homeostasis membrane protein CopD -
I6J98_RS09620 2014382..2014723 + 342 WP_000976484.1 YebY family protein -
- 2014751..2015022 - 272 - - Antitoxin
- 2014882..2014984 + 103 - - Toxin
I6J98_RS09625 2015119..2015775 + 657 WP_000812752.1 protein-serine/threonine phosphatase -
I6J98_RS09630 2015776..2015967 - 192 WP_001296140.1 YebW family protein -
I6J98_RS09635 2016072..2016308 - 237 WP_001295499.1 DUF1480 family protein -
I6J98_RS09640 2016426..2017865 - 1440 WP_204088926.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T190698 NZ_CP069501:2014882-2014984 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT190698 NZ_CP069501:c2015022-2014751 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References