Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/YafQ-RelB |
Location | 3746..4295 | Replicon | plasmid unnamed1 |
Accession | NZ_CP069497 | ||
Organism | Acinetobacter pittii strain FDAARGOS_1217 |
Toxin (Protein)
Gene name | relE | Uniprot ID | N9KJ78 |
Locus tag | I6J47_RS18350 | Protein ID | WP_000176412.1 |
Coordinates | 4005..4295 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | N9KCM7 |
Locus tag | I6J47_RS18345 | Protein ID | WP_005140357.1 |
Coordinates | 3746..4021 (+) | Length | 92 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6J47_RS18320 | 1..9060 | - | 9060 | WP_000179382.1 | MobA/MobL family protein | - |
I6J47_RS18325 | 666..1442 | + | 777 | WP_000191151.1 | hypothetical protein | - |
I6J47_RS18330 | 1667..2866 | + | 1200 | WP_002072939.1 | hypothetical protein | - |
I6J47_RS18335 | 2939..3181 | - | 243 | WP_001015364.1 | hypothetical protein | - |
I6J47_RS18340 | 3330..3554 | + | 225 | WP_002072934.1 | hypothetical protein | - |
I6J47_RS18345 | 3746..4021 | + | 276 | WP_005140357.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
I6J47_RS18350 | 4005..4295 | + | 291 | WP_000176412.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
I6J47_RS18355 | 4343..4489 | - | 147 | WP_000192351.1 | hypothetical protein | - |
I6J47_RS18360 | 4486..5007 | - | 522 | WP_000999915.1 | hypothetical protein | - |
I6J47_RS18365 | 5532..5849 | - | 318 | WP_005065053.1 | hypothetical protein | - |
I6J47_RS18370 | 6200..6766 | - | 567 | WP_000858429.1 | plasmid replication DNA-binding protein | - |
I6J47_RS18375 | 6830..7711 | - | 882 | WP_005804946.1 | replication initiation protein RepM | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..9060 | 9060 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11187.12 Da Isoelectric Point: 6.9783
>T190657 WP_000176412.1 NZ_CP069497:4005-4295 [Acinetobacter pittii]
MTLTIRYKKQFKKDFKRVSSNPKLKKGLLILKDLIDEHLVKTGTVPDEYLPHPLIGEWKPHMECHILPDLLLIWDVDEDN
NELILARIGSHSELFG
MTLTIRYKKQFKKDFKRVSSNPKLKKGLLILKDLIDEHLVKTGTVPDEYLPHPLIGEWKPHMECHILPDLLLIWDVDEDN
NELILARIGSHSELFG
Download Length: 291 bp
>T190657 NZ_CP091518:647429-647698 [Kingella kingae]
ATGAGCAGAGAAATTATTTTTCAAGGGCAGTTTAAGCGAGATGTGAAAAAGCAGTTTTTAGAGCTTGCGACAGTGGAATG
GGCAGAAGTTTTAACTTGTTTGGTAAATGATTTGCCGCTTGCTGAAAAATATCGCGACCATGCGCTTGTGAATGACAAAA
ACGGATACAGAGACTGCCATATCAAGCCTGATTTGGTTTTAATTTACGGCAGGAAAGAAAACGCCTTGATACTTGTTCGG
TTAGGTTCTCATTCCGAGATATTTGGCTAA
ATGAGCAGAGAAATTATTTTTCAAGGGCAGTTTAAGCGAGATGTGAAAAAGCAGTTTTTAGAGCTTGCGACAGTGGAATG
GGCAGAAGTTTTAACTTGTTTGGTAAATGATTTGCCGCTTGCTGAAAAATATCGCGACCATGCGCTTGTGAATGACAAAA
ACGGATACAGAGACTGCCATATCAAGCCTGATTTGGTTTTAATTTACGGCAGGAAAGAAAACGCCTTGATACTTGTTCGG
TTAGGTTCTCATTCCGAGATATTTGGCTAA
Antitoxin
Download Length: 92 a.a. Molecular weight: 10290.65 Da Isoelectric Point: 4.6702
>AT190657 WP_005140357.1 NZ_CP069497:3746-4021 [Acinetobacter pittii]
MNTLAKKDEYVRARVPNELKVQAERILKEVGLNTTDAIRLLLTQVVNRGGFPLELRTPNRTTIEAMNSVAEPKKFSSAQE
LFTDLEDDTDD
MNTLAKKDEYVRARVPNELKVQAERILKEVGLNTTDAIRLLLTQVVNRGGFPLELRTPNRTTIEAMNSVAEPKKFSSAQE
LFTDLEDDTDD
Download Length: 276 bp
>AT190657 NZ_CP091518:647148-647432 [Kingella kingae]
ATGAGCGCAATAAATTTTAATATCCGTATGGATAAAAGTTTGAAAGAACGCGCATTTCCAGTCATTGAGAGCTACGGATT
AACGCCAGCACAAGCAGTCAAACTGTTTTTTAATCAGATTGCTACTACCCAAACCATTCCCATTTCATTTGAACACAACG
TAAACCGCATTCCTAATGCAATCACACGTAAAGCGATTGAAGATGCGGAATCCGAATTTGAGACAGCCAAACGCTATAAA
ACCGTTGAAGAAGCTATTGCAGCAATGCAGGAATTGGCGAAATGA
ATGAGCGCAATAAATTTTAATATCCGTATGGATAAAAGTTTGAAAGAACGCGCATTTCCAGTCATTGAGAGCTACGGATT
AACGCCAGCACAAGCAGTCAAACTGTTTTTTAATCAGATTGCTACTACCCAAACCATTCCCATTTCATTTGAACACAACG
TAAACCGCATTCCTAATGCAATCACACGTAAAGCGATTGAAGATGCGGAATCCGAATTTGAGACAGCCAAACGCTATAAA
ACCGTTGAAGAAGCTATTGCAGCAATGCAGGAATTGGCGAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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