Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC(toxin) |
| Location | 57773..58410 | Replicon | chromosome |
| Accession | NZ_CP069495 | ||
| Organism | Kytococcus sedentarius strain FDAARGOS_1200 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | I6J30_RS00310 | Protein ID | WP_204159995.1 |
| Coordinates | 58018..58410 (+) | Length | 131 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | I6J30_RS00305 | Protein ID | WP_041290823.1 |
| Coordinates | 57773..58021 (+) | Length | 83 a.a. |
Genomic Context
Location: 55541..56863 (1323 bp)
Type: Others
Protein ID: WP_049758591.1
Type: Others
Protein ID: WP_049758591.1
Location: 57773..58021 (249 bp)
Type: Antitoxin
Protein ID: WP_041290823.1
Type: Antitoxin
Protein ID: WP_041290823.1
Location: 58018..58410 (393 bp)
Type: Toxin
Protein ID: WP_204159995.1
Type: Toxin
Protein ID: WP_204159995.1
Location: 53541..54785 (1245 bp)
Type: Others
Protein ID: WP_204159992.1
Type: Others
Protein ID: WP_204159992.1
Location: 54786..55145 (360 bp)
Type: Others
Protein ID: WP_204159993.1
Type: Others
Protein ID: WP_204159993.1
Location: 56899..57711 (813 bp)
Type: Others
Protein ID: WP_204159994.1
Type: Others
Protein ID: WP_204159994.1
Location: 58415..58711 (297 bp)
Type: Others
Protein ID: Protein_62
Type: Others
Protein ID: Protein_62
Location: 58805..59482 (678 bp)
Type: Others
Protein ID: WP_204159996.1
Type: Others
Protein ID: WP_204159996.1
Location: 59532..59873 (342 bp)
Type: Others
Protein ID: WP_204159997.1
Type: Others
Protein ID: WP_204159997.1
Location: 59909..60418 (510 bp)
Type: Others
Protein ID: WP_204160919.1
Type: Others
Protein ID: WP_204160919.1
Location: 61811..62872 (1062 bp)
Type: Others
Protein ID: WP_204159998.1
Type: Others
Protein ID: WP_204159998.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I6J30_RS00285 | 53541..54785 | - | 1245 | WP_204159992.1 | cupin-like domain-containing protein | - |
| I6J30_RS00290 | 54786..55145 | - | 360 | WP_204159993.1 | BatC protein | - |
| I6J30_RS00295 | 55541..56863 | + | 1323 | WP_049758591.1 | replicative DNA helicase | - |
| I6J30_RS00300 | 56899..57711 | - | 813 | WP_204159994.1 | fused MFS/spermidine synthase | - |
| I6J30_RS00305 | 57773..58021 | + | 249 | WP_041290823.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| I6J30_RS00310 | 58018..58410 | + | 393 | WP_204159995.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| I6J30_RS00315 | 58415..58711 | - | 297 | Protein_62 | HNH endonuclease | - |
| I6J30_RS00320 | 58805..59482 | - | 678 | WP_204159996.1 | maleylpyruvate isomerase family mycothiol-dependent enzyme | - |
| I6J30_RS00325 | 59532..59873 | - | 342 | WP_204159997.1 | DUF2200 domain-containing protein | - |
| I6J30_RS00330 | 59909..60418 | - | 510 | WP_204160919.1 | HNH endonuclease | - |
| I6J30_RS00335 | 61811..62872 | - | 1062 | WP_204159998.1 | lipoate--protein ligase family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 131 a.a. Molecular weight: 13783.70 Da Isoelectric Point: 4.5112
>T190651 WP_204159995.1 NZ_CP069495:58018-58410 [Kytococcus sedentarius]
VIVDSSAIVAILLAEPERQVLLEAIQQAPKVAMTAASYLEVGMVVDGRGNPVLSRQYDALLEALGIEVVDTTAEQARVAR
AAHRDFGRGSGHPARLNFGDCLSYAAAVQDGVPLLFKGDDFIHTDVTPAL
VIVDSSAIVAILLAEPERQVLLEAIQQAPKVAMTAASYLEVGMVVDGRGNPVLSRQYDALLEALGIEVVDTTAEQARVAR
AAHRDFGRGSGHPARLNFGDCLSYAAAVQDGVPLLFKGDDFIHTDVTPAL
Download Length: 393 bp
>T190651 NZ_CP091515:346692-346865 [Snodgrassella alvi wkB2]
ATGAAAATACAAAAATTTTTAAACTTATTAATTTCTCAAGGAGTAAAAACTAAAGATGGCACTAAACACATAAAACTTTA
CTATAATGGTAAGCAATCGACTTTACCCAGACACCCCAGTAAAGAGATTCCAAAGCGGCTGGTTGAAAAAATCAAAAAGC
AGTTGGGATTATAA
ATGAAAATACAAAAATTTTTAAACTTATTAATTTCTCAAGGAGTAAAAACTAAAGATGGCACTAAACACATAAAACTTTA
CTATAATGGTAAGCAATCGACTTTACCCAGACACCCCAGTAAAGAGATTCCAAAGCGGCTGGTTGAAAAAATCAAAAAGC
AGTTGGGATTATAA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9004.15 Da Isoelectric Point: 4.6158
>AT190651 WP_041290823.1 NZ_CP069495:57773-58021 [Kytococcus sedentarius]
MALTIKNDRVCDLAREAAQRSGQSQVSVIEQALERYLADHAEPVGRRVDEVLARIDASLAPGDAAAMRVELDRLYDERGL
PA
MALTIKNDRVCDLAREAAQRSGQSQVSVIEQALERYLADHAEPVGRRVDEVLARIDASLAPGDAAAMRVELDRLYDERGL
PA
Download Length: 249 bp
>AT190651 NZ_CP091515:346976-347458 [Snodgrassella alvi wkB2]
ATGGTTCAAATATCAGAAATGTATTCTCAAAATACAAGCTGTAAAACAGATATGTCTTACAGCGCATTAATACAAAAACA
AGCAAATTCATATGTAGTCACTTTTCGCGACTTACCAGAAGCATTAACCTGTGGAGATACGCTTGAAGAAGCACGTATTA
TGGCCGCAGATGCGTTACTTACTGCTTTAGAATTTTATTTTGAAGACCGTCGGCCAGTGCCTATACCTTCGAAAATGCAG
AAAGGTGAAGAATTGATTTCTTTACCTCCTAGTGTTACTGCAAAAGTACTTTTACTTAATGAAATGATTAAGCAAAATGT
TTCCAATGCAGAGTTAGCCAGACGTTTACTTACACGTCCTCAGGATGTTCAAAGGCTTACTAATCTTCGTCATGCAACTA
AAATTGATGCTATTAACGCTGCATTAAATCAACTAGGTAAACAACTACATATTAGTTTAATACCCATTCATCATTCAGCA
TAA
ATGGTTCAAATATCAGAAATGTATTCTCAAAATACAAGCTGTAAAACAGATATGTCTTACAGCGCATTAATACAAAAACA
AGCAAATTCATATGTAGTCACTTTTCGCGACTTACCAGAAGCATTAACCTGTGGAGATACGCTTGAAGAAGCACGTATTA
TGGCCGCAGATGCGTTACTTACTGCTTTAGAATTTTATTTTGAAGACCGTCGGCCAGTGCCTATACCTTCGAAAATGCAG
AAAGGTGAAGAATTGATTTCTTTACCTCCTAGTGTTACTGCAAAAGTACTTTTACTTAATGAAATGATTAAGCAAAATGT
TTCCAATGCAGAGTTAGCCAGACGTTTACTTACACGTCCTCAGGATGTTCAAAGGCTTACTAATCTTCGTCATGCAACTA
AAATTGATGCTATTAACGCTGCATTAAATCAACTAGGTAAACAACTACATATTAGTTTAATACCCATTCATCATTCAGCA
TAA