Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
| Location | 3672172..3672692 | Replicon | chromosome |
| Accession | NZ_CP069488 | ||
| Organism | Escherichia coli strain FDAARGOS_1264 | ||
Toxin (Protein)
| Gene name | ccdB | Uniprot ID | A0A061KX66 |
| Locus tag | I6J94_RS17960 | Protein ID | WP_001160964.1 |
| Coordinates | 3672172..3672456 (-) | Length | 95 a.a. |
Antitoxin (Protein)
| Gene name | ccdA | Uniprot ID | V0VEX8 |
| Locus tag | I6J94_RS17965 | Protein ID | WP_000125566.1 |
| Coordinates | 3672459..3672692 (-) | Length | 78 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 95 a.a. Molecular weight: 10692.54 Da Isoelectric Point: 10.3030
>T190643 WP_001160964.1 NZ_CP069488:c3672456-3672172 [Escherichia coli]
MQFTVYRSRGRNAAFPFVIDVTSDIIGEINRRIVIPLTPIERFSRIRPPERLNPILLLIDGKEYVLMTHETATVPVNALG
TKFCDASAHRTLIK
MQFTVYRSRGRNAAFPFVIDVTSDIIGEINRRIVIPLTPIERFSRIRPPERLNPILLLIDGKEYVLMTHETATVPVNALG
TKFCDASAHRTLIK
Download Length: 285 bp
>T190643 NZ_CP091509:1904020-1904415 [Neisseria dumasiana]
ATGCGCTACCTTTTGGATACCAACATTGTGAGCCATATCCTGCGCCGGCAACCCAATGTGATGGCAAGATTGCAAAGCGT
GCCGATGTCTGATCTATATATTTCGGCGGTTACTCATGCCGAATTGATGTACGGCTTGGCGAAAAAACCTGATGCGGCCA
AGCTGCATCGTGCCGTGCATGAACTTTTATTGCGTATAGGCGTATTACCGTTCGACGAACAAGCAAGCACGCATTACGGA
AAATTTAAAGCACAGGCAAAGCAGTCGGGTAAAAACTTGGCATCTTTAGATATGATGATTGCCGCCCATGCTTCCGCCGT
AAGCGCAGTATTGGTCAGCAACGATGCCGCTTTCCAACAGATTGCTGATTTATCGGTGGAAGACTGGACGAAATAA
ATGCGCTACCTTTTGGATACCAACATTGTGAGCCATATCCTGCGCCGGCAACCCAATGTGATGGCAAGATTGCAAAGCGT
GCCGATGTCTGATCTATATATTTCGGCGGTTACTCATGCCGAATTGATGTACGGCTTGGCGAAAAAACCTGATGCGGCCA
AGCTGCATCGTGCCGTGCATGAACTTTTATTGCGTATAGGCGTATTACCGTTCGACGAACAAGCAAGCACGCATTACGGA
AAATTTAAAGCACAGGCAAAGCAGTCGGGTAAAAACTTGGCATCTTTAGATATGATGATTGCCGCCCATGCTTCCGCCGT
AAGCGCAGTATTGGTCAGCAACGATGCCGCTTTCCAACAGATTGCTGATTTATCGGTGGAAGACTGGACGAAATAA
Antitoxin
Download Length: 78 a.a. Molecular weight: 8530.53 Da Isoelectric Point: 5.8062
>AT190643 WP_000125566.1 NZ_CP069488:c3672692-3672459 [Escherichia coli]
MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAALNQLADETGCFSDEYRSF
MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAALNQLADETGCFSDEYRSF
Download Length: 234 bp
>AT190643 NZ_CP091509:1903771-1904016 [Neisseria dumasiana]
ATGCAAACCGCCAAACTTTTTCAAAACGGCCGCAGCCAAGCAGTACGGCTGCCTGCAGCATTCCGATTTACGGGTGATGA
AGTGTATATCCGCCGAGATGAAGCCACGGGCGATGTGATTTTGTCGCAACGTCCGAGCGACTGGCAGGGTTTTATCGCCG
CAGCATCGGAGCTTGACGAAAGCGATACCATTGAACGCGATACCTCCATACAGCAACGCGATCCGTTTGCAGACTGGCAG
GAATAA
ATGCAAACCGCCAAACTTTTTCAAAACGGCCGCAGCCAAGCAGTACGGCTGCCTGCAGCATTCCGATTTACGGGTGATGA
AGTGTATATCCGCCGAGATGAAGCCACGGGCGATGTGATTTTGTCGCAACGTCCGAGCGACTGGCAGGGTTTTATCGCCG
CAGCATCGGAGCTTGACGAAAGCGATACCATTGAACGCGATACCTCCATACAGCAACGCGATCCGTTTGCAGACTGGCAG
GAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A061KX66 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A7U9LTM9 |