190251

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 5281452..5281957 Replicon chromosome
Accession NZ_CP069352
Organism Pseudomonas granadensis isolate CT364

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JN757_RS23020 Protein ID WP_203419411.1
Coordinates 5281703..5281957 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JN757_RS23015 Protein ID WP_203419410.1
Coordinates 5281452..5281706 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN757_RS22985 5276615..5276875 - 261 WP_203419406.1 hypothetical protein -
JN757_RS22990 5277046..5277375 + 330 WP_203419407.1 hypothetical protein -
JN757_RS22995 5277394..5277762 - 369 WP_090286060.1 PH domain-containing protein -
JN757_RS23000 5277955..5278311 + 357 WP_203422136.1 hypothetical protein -
JN757_RS23005 5278428..5279231 + 804 WP_203419408.1 hypothetical protein -
JN757_RS23010 5279304..5281223 + 1920 WP_203419409.1 alkaline phosphatase family protein -
JN757_RS23015 5281452..5281706 + 255 WP_203419410.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
JN757_RS23020 5281703..5281957 + 255 WP_203419411.1 Txe/YoeB family addiction module toxin Toxin
JN757_RS23025 5281951..5283138 - 1188 WP_203419412.1 aspartate aminotransferase family protein -
JN757_RS23030 5283240..5284169 + 930 WP_203419413.1 LysR family transcriptional regulator -
JN757_RS23035 5284301..5285002 + 702 WP_203419414.1 hypothetical protein -
JN757_RS23040 5285258..5285749 - 492 WP_090286073.1 RidA family protein -
JN757_RS23045 5286061..5286948 - 888 WP_090286075.1 heme o synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9955.58 Da        Isoelectric Point: 9.0629

>T190251 WP_203419411.1 NZ_CP069352:5281703-5281957 [Pseudomonas granadensis]
MKIQFTPTGWEDYLWFQQNDKAGLKRINLLIKAIKREPFEGVGKPEALKHNMSGLWSRRITAEHRLVYMIEDGEVCVISC
RYHY

Download         Length: 255 bp

>T190251 NZ_CP091198:1764331-1764600 [Enterococcus faecalis]
ATGTCCTATCGATTAGAATTTACTCCTGATGTAAAAAAACAGTTAAAAAAAATGGATAAATATCAAGCGACATTGCTAAC
AAGATGGTTGTATCGAAATATTGATGGAACGGCCAATCCTAGAGAGCATGGAAAAGCTTTATCAGCAAATCGTGCAGGTC
AGTGGCGATATAGGATAGGGAATTATCGTGTCATTGTAGAAATAGAAGATGAACGTCTTGTTGTTACAGCCATTCAGGTT
GGCCACAGAAGAAATGTTTACGACAAATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9534.93 Da        Isoelectric Point: 7.0125

>AT190251 WP_203419410.1 NZ_CP069352:5281452-5281706 [Pseudomonas granadensis]
MQTINYTTARAHLAETMDRVNEDRAPLLVTRQKGEPVVMMSLSDYNALEETAYLLRSPANAERLMKSINELRAGKAKARQ
LIEE

Download         Length: 255 bp

>AT190251 NZ_CP091198:1764110-1764331 [Enterococcus faecalis]
ATGATTACTGTAAGAGTGAGTGATGAAGAAAAAGAATGGCTTTCTTACATGGCAGAATTTTTCGGTGTGACGTTGTCGGA
TTTGTTAAAAAGCTATTCAATGGAACAATTAGAAGATGAGTACGATAAACAAACAGCAGAAATTGCTCACAAACGATGGA
TTGAGCAAGGAAAAGAAACAATTTCTATGGACGAAATATTAAATGAGTTTGGTGGATTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References