Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 2478582..2479186 Replicon chromosome
Accession NZ_CP069352
Organism Pseudomonas granadensis isolate CT364

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag JN757_RS10860 Protein ID WP_203421558.1
Coordinates 2478893..2479186 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag JN757_RS10855 Protein ID WP_203421557.1
Coordinates 2478582..2478890 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JN757_RS10830 2474761..2475780 - 1020 WP_203421553.1 alpha/beta hydrolase -
JN757_RS10835 2475942..2476841 + 900 WP_203421554.1 LysR family transcriptional regulator -
JN757_RS10840 2477015..2477287 + 273 WP_090282708.1 ribbon-helix-helix domain-containing protein -
JN757_RS10845 2477289..2477564 + 276 WP_203421555.1 type II toxin-antitoxin system RelE/ParE family toxin -
JN757_RS10850 2477664..2478461 + 798 WP_203421556.1 class I SAM-dependent methyltransferase -
JN757_RS10855 2478582..2478890 - 309 WP_203421557.1 putative addiction module antidote protein Antitoxin
JN757_RS10860 2478893..2479186 - 294 WP_203421558.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JN757_RS10865 2480122..2480814 - 693 WP_203421559.1 N-acetyltransferase -
JN757_RS10870 2480811..2482001 - 1191 WP_203421560.1 GNAT family N-acetyltransferase -
JN757_RS10875 2482006..2482695 - 690 WP_203421561.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(23-89)

Antitoxin

Uncharacterized protein HI1420

(4-93)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10683.23 Da        Isoelectric Point: 10.7543

>T190248 WP_203421558.1 NZ_CP069352:c2479186-2478893 [Pseudomonas granadensis]
MTYLIQQTATFQAWHRSIRDLQAKVAIARRIDRASTGNLGDTKSVGDGVSEMRLDIGPGYRVYFTIRNGAVIILLAGGDK
SSQSADIRRAQKMAKEV

Download         Length: 294 bp

>T190248 NZ_CP091198:1178519-1178662 [Enterococcus faecalis]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCGG
TTCTTTTATCGCGACTTTAATCTTCGGAATCCTAAAGGTTGTTAAAGAAGACAAGAAAAAATAA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10964.49 Da        Isoelectric Point: 6.0606

>AT190248 WP_203421557.1 NZ_CP069352:c2478890-2478582 [Pseudomonas granadensis]
MSQALTNFDMASLLDSDEAISEYLSQVLADGDNEEFLRAIGHVLKARGMTQIAKSSGMGRESLYKAFAPGAKPRFDTVLK
VIHALGMDLCAQPGHVINHSAS

Download         Length: 309 bp

>AT190248 NZ_CP091198:c1178852-1178594 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATTGATGGTCTTTTGATGGTCGTTGTGCTATA
ATAGCATTGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCGATTTTGTTACAA
AAAATAACCGTACTCAGTCAAAGTAAACGGTTATTTTTTCTTGTCTTCTTTAACAACCTTTAGGATTCCGAAGATTAAAG
TCGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References