Detailed information of TA system TA190243

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 361398..361948
• Replicon: chromosome
• Accession: NZ_CP069350
• Organism: Shewanella sp. LZH-2

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: JM642_RS01770
• Protein ID: WP_203432566.1
• Coordinates: 361398..361697 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: JM642_RS01775
• Protein ID: WP_203432567.1
• Coordinates: 361706..361948 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JM642_RS01750	357013..358200	+	1188	WP_203433697.1	benzoate/H(+) symporter BenE family transporter	-
JM642_RS01755	358258..358713	-	456	WP_203432563.1	GNAT family N-acetyltransferase	-
JM642_RS01760	358986..359660	+	675	WP_203432564.1	hypothetical protein	-
JM642_RS01765	359836..360753	-	918	WP_203432565.1	hypothetical protein	-
JM642_RS01770	361398..361697	-	300	WP_203432566.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JM642_RS01775	361706..361948	-	243	WP_203432567.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
JM642_RS01780	362142..362885	-	744	WP_203432568.1	hypothetical protein	-
JM642_RS01785	362896..364158	-	1263	WP_203432569.1	beta-ketoacyl-ACP synthase	-
JM642_RS01790	364159..364884	-	726	WP_203432570.1	3-ketoacyl-ACP reductase FabG2	-
JM642_RS01795	364985..365485	-	501	WP_172588057.1	hotdog family protein	-
JM642_RS01800	365533..366750	-	1218	WP_203432571.1	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-64)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11533.30 Da
• Isoelectric Point: 9.6121

>T190243 WP_203432566.1 NZ_CP069350:c361697-361398 [Shewanella sp. LZH-2]
MNNKRYKLSKLAQTHLLKIKDYTLQHFSESQWHKYKESLISGLQMLADNPGLGRSCNDIYPNGFYFPIGKHTAYFTKEDD
FILIVALLGQPQLPQHHLK

Nucleotide

• Length: 300 bp

>T190243 NZ_CP091198:c1000327-1000226 [Enterococcus faecalis]
TTGTCAATCGAAGCGGCATTGGAATTGATGATTAGTTTTGCAGCGTTTGTTGCACTACTGATTTTCGGTATCCTTGAAGC
AACGAAAAACAATAAAAAATAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8927.15 Da
• Isoelectric Point: 5.0621

>AT190243 WP_203432567.1 NZ_CP069350:c361948-361706 [Shewanella sp. LZH-2]
MQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLSAL

Nucleotide

• Length: 243 bp

>AT190243 NZ_CP091198:1000107-1000281 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTT
TTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTATTTTTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAA
TCAGTAGTGCAACAA