Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2025264..2025428 | Replicon | chromosome |
| Accession | NZ_CP069319 | ||
| Organism | Kosakonia cowanii strain Pa82 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2025324..2025426 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2025264..2025428 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JMT66_RS09680 (JMT66_09650) | 2020473..2022527 | + | 2055 | WP_200133678.1 | oligopeptidase B | - |
| JMT66_RS09685 (JMT66_09655) | 2022528..2023190 | - | 663 | WP_094419595.1 | exodeoxyribonuclease X | - |
| JMT66_RS09690 (JMT66_09660) | 2023202..2023432 | - | 231 | WP_042714382.1 | DNA polymerase III subunit theta | - |
| JMT66_RS09695 (JMT66_09665) | 2023569..2023943 | + | 375 | WP_200580091.1 | CopC domain-containing protein YobA | - |
| JMT66_RS09700 (JMT66_09670) | 2023945..2024814 | + | 870 | WP_200580092.1 | copper homeostasis membrane protein CopD | - |
| JMT66_RS09705 (JMT66_09675) | 2024833..2025177 | + | 345 | WP_200580093.1 | YebY family protein | - |
| - | 2025264..2025428 | - | 165 | - | - | Antitoxin |
| - | 2025324..2025426 | + | 103 | - | - | Toxin |
| JMT66_RS09710 (JMT66_09680) | 2025504..2026586 | - | 1083 | WP_232045371.1 | tyrosine-type recombinase/integrase | - |
| JMT66_RS09715 (JMT66_09685) | 2026558..2026827 | - | 270 | WP_232045372.1 | excisionase | - |
| JMT66_RS09720 (JMT66_09690) | 2026893..2027135 | - | 243 | WP_187799165.1 | DUF4060 family protein | - |
| JMT66_RS09725 (JMT66_09695) | 2027132..2027308 | - | 177 | WP_167552474.1 | hypothetical protein | - |
| JMT66_RS09730 (JMT66_09700) | 2027343..2028419 | - | 1077 | WP_232045373.1 | RecT family recombinase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2004433..2092486 | 88053 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T190141 NZ_CP069319:2025324-2025426 [Kosakonia cowanii]
GCAAGGCGACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT
GCAAGGCGACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 165 bp
>AT190141 NZ_CP069319:c2025428-2025264 [Kosakonia cowanii]
ATAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTTAGTCGCCTTGCACCTTAAGAATAGATGACGACACCAGCTTTTCCAGTCCGCGACAAATGTGGTCAG
AAAAA
ATAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTTAGTCGCCTTGCACCTTAAGAATAGATGACGACACCAGCTTTTCCAGTCCGCGACAAATGTGGTCAG
AAAAA
