Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 821588..822251 | Replicon | chromosome |
Accession | NZ_CP069319 | ||
Organism | Kosakonia cowanii strain Pa82 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | - |
Locus tag | JMT66_RS03920 | Protein ID | WP_054803578.1 |
Coordinates | 821835..822251 (+) | Length | 139 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | - |
Locus tag | JMT66_RS03915 | Protein ID | WP_200579605.1 |
Coordinates | 821588..821854 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JMT66_RS03895 (JMT66_03885) | 817146..818579 | - | 1434 | WP_042718305.1 | 6-phospho-beta-glucosidase | - |
JMT66_RS03900 (JMT66_03890) | 818696..819424 | - | 729 | WP_023481032.1 | MurR/RpiR family transcriptional regulator | - |
JMT66_RS03905 (JMT66_03895) | 819651..820310 | + | 660 | WP_200579607.1 | hemolysin III family protein | - |
JMT66_RS03910 (JMT66_03900) | 820361..821341 | - | 981 | WP_200579606.1 | tRNA-modifying protein YgfZ | - |
JMT66_RS03915 (JMT66_03905) | 821588..821854 | + | 267 | WP_200579605.1 | FAD assembly factor SdhE | Antitoxin |
JMT66_RS03920 (JMT66_03910) | 821835..822251 | + | 417 | WP_054803578.1 | protein YgfX | Toxin |
JMT66_RS03925 (JMT66_03915) | 822269..822790 | - | 522 | WP_094422004.1 | flavodoxin FldB | - |
JMT66_RS03930 (JMT66_03920) | 822890..823786 | + | 897 | WP_023480693.1 | site-specific tyrosine recombinase XerD | - |
JMT66_RS03935 (JMT66_03925) | 823811..824521 | + | 711 | WP_042718296.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
JMT66_RS03940 (JMT66_03930) | 824527..826260 | + | 1734 | WP_200579604.1 | single-stranded-DNA-specific exonuclease RecJ | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 16454.36 Da Isoelectric Point: 10.7346
>T190140 WP_054803578.1 NZ_CP069319:821835-822251 [Kosakonia cowanii]
VVLWQSELRVSWRAQWLSLLLHGFVAALILLMPWPLSYTPVWLLLLSLVVFDSVRSQRRINACHGEIKLLMDSRLRWQGE
EWDIVGTPWMLRSGMMLRLRREEDGRRQHLWLASDSMDAQEWRDLRRMILQKPAQGLH
VVLWQSELRVSWRAQWLSLLLHGFVAALILLMPWPLSYTPVWLLLLSLVVFDSVRSQRRINACHGEIKLLMDSRLRWQGE
EWDIVGTPWMLRSGMMLRLRREEDGRRQHLWLASDSMDAQEWRDLRRMILQKPAQGLH
Download Length: 417 bp
>T190140 NZ_CP091121:4519358-4519648 [Serratia ureilytica]
ATGATTAAATCTTTCCGCGATCGCTATCTGGAGCAGTTCTATCTGGAAGGCAGGCGCAGCCGTCTTATCCCCGGCGCGCT
CGAGCGGCAGTTGGCCAGAAAGCTCGATATGTTAGCCGCCGCGCAGCAAGAGCGTGATTTGCATCACCCCAAGGGTAACT
ATTACAAGCGGCTATCCGGGCCATTTCAGGGATGGTCGAGTCTGCGCGTCAATATGCACTGGCGGCTGATGTTCCAGTGG
CGGCATGATGCCGCCGAAAAAATTTACCTCGATCCTCACCAAGATACCTGA
ATGATTAAATCTTTCCGCGATCGCTATCTGGAGCAGTTCTATCTGGAAGGCAGGCGCAGCCGTCTTATCCCCGGCGCGCT
CGAGCGGCAGTTGGCCAGAAAGCTCGATATGTTAGCCGCCGCGCAGCAAGAGCGTGATTTGCATCACCCCAAGGGTAACT
ATTACAAGCGGCTATCCGGGCCATTTCAGGGATGGTCGAGTCTGCGCGTCAATATGCACTGGCGGCTGATGTTCCAGTGG
CGGCATGATGCCGCCGAAAAAATTTACCTCGATCCTCACCAAGATACCTGA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10555.03 Da Isoelectric Point: 6.2199
>AT190140 WP_200579605.1 NZ_CP069319:821588-821854 [Kosakonia cowanii]
MDITNKARIHWACRRGMRELDISIMPFFEHEYDSLSDNDKRLFVRLLENDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI
MDITNKARIHWACRRGMRELDISIMPFFEHEYDSLSDNDKRLFVRLLENDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI
Download Length: 267 bp
>AT190140 NZ_CP091121:4519663-4519986 [Serratia ureilytica]
ATGTTGGAAACCACGACTCGCGAACCCACCACGGTGGGAGAAGTGCTGCAGGAAGAATATTTAACGCCGTTAGGCATCGG
CCAAGAAGAACTGGCAAAGGTATTGGGCGTCACCCGCGCCACCGTCAATCGCCTGTGCAACGGGCATCGACGCATGAGCG
TTGCCGAGGCCAATCTGTTTGCCGATCTGTTCGAAACGACCGCCGACTTTTGGCTAAACCTGCAGGCGGCACACGATCGC
TGGGAAGCCAGACAGGCCGATGCGCAGCGTGTGCGGCTGCGGCCAATCAAAGAAATACTGGGACGCAATATCACTCATGC
ATGA
ATGTTGGAAACCACGACTCGCGAACCCACCACGGTGGGAGAAGTGCTGCAGGAAGAATATTTAACGCCGTTAGGCATCGG
CCAAGAAGAACTGGCAAAGGTATTGGGCGTCACCCGCGCCACCGTCAATCGCCTGTGCAACGGGCATCGACGCATGAGCG
TTGCCGAGGCCAATCTGTTTGCCGATCTGTTCGAAACGACCGCCGACTTTTGGCTAAACCTGCAGGCGGCACACGATCGC
TGGGAAGCCAGACAGGCCGATGCGCAGCGTGTGCGGCTGCGGCCAATCAAAGAAATACTGGGACGCAATATCACTCATGC
ATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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