Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 821588..822251 Replicon chromosome
Accession NZ_CP069319
Organism Kosakonia cowanii strain Pa82

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JMT66_RS03920 Protein ID WP_054803578.1
Coordinates 821835..822251 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JMT66_RS03915 Protein ID WP_200579605.1
Coordinates 821588..821854 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JMT66_RS03895 (JMT66_03885) 817146..818579 - 1434 WP_042718305.1 6-phospho-beta-glucosidase -
JMT66_RS03900 (JMT66_03890) 818696..819424 - 729 WP_023481032.1 MurR/RpiR family transcriptional regulator -
JMT66_RS03905 (JMT66_03895) 819651..820310 + 660 WP_200579607.1 hemolysin III family protein -
JMT66_RS03910 (JMT66_03900) 820361..821341 - 981 WP_200579606.1 tRNA-modifying protein YgfZ -
JMT66_RS03915 (JMT66_03905) 821588..821854 + 267 WP_200579605.1 FAD assembly factor SdhE Antitoxin
JMT66_RS03920 (JMT66_03910) 821835..822251 + 417 WP_054803578.1 protein YgfX Toxin
JMT66_RS03925 (JMT66_03915) 822269..822790 - 522 WP_094422004.1 flavodoxin FldB -
JMT66_RS03930 (JMT66_03920) 822890..823786 + 897 WP_023480693.1 site-specific tyrosine recombinase XerD -
JMT66_RS03935 (JMT66_03925) 823811..824521 + 711 WP_042718296.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JMT66_RS03940 (JMT66_03930) 824527..826260 + 1734 WP_200579604.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16454.36 Da        Isoelectric Point: 10.7346

>T190140 WP_054803578.1 NZ_CP069319:821835-822251 [Kosakonia cowanii]
VVLWQSELRVSWRAQWLSLLLHGFVAALILLMPWPLSYTPVWLLLLSLVVFDSVRSQRRINACHGEIKLLMDSRLRWQGE
EWDIVGTPWMLRSGMMLRLRREEDGRRQHLWLASDSMDAQEWRDLRRMILQKPAQGLH

Download         Length: 417 bp

>T190140 NZ_CP091121:4519358-4519648 [Serratia ureilytica]
ATGATTAAATCTTTCCGCGATCGCTATCTGGAGCAGTTCTATCTGGAAGGCAGGCGCAGCCGTCTTATCCCCGGCGCGCT
CGAGCGGCAGTTGGCCAGAAAGCTCGATATGTTAGCCGCCGCGCAGCAAGAGCGTGATTTGCATCACCCCAAGGGTAACT
ATTACAAGCGGCTATCCGGGCCATTTCAGGGATGGTCGAGTCTGCGCGTCAATATGCACTGGCGGCTGATGTTCCAGTGG
CGGCATGATGCCGCCGAAAAAATTTACCTCGATCCTCACCAAGATACCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.03 Da        Isoelectric Point: 6.2199

>AT190140 WP_200579605.1 NZ_CP069319:821588-821854 [Kosakonia cowanii]
MDITNKARIHWACRRGMRELDISIMPFFEHEYDSLSDNDKRLFVRLLENDDPDLFNWLMNHGKPQDAELQRMVQLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT190140 NZ_CP091121:4519663-4519986 [Serratia ureilytica]
ATGTTGGAAACCACGACTCGCGAACCCACCACGGTGGGAGAAGTGCTGCAGGAAGAATATTTAACGCCGTTAGGCATCGG
CCAAGAAGAACTGGCAAAGGTATTGGGCGTCACCCGCGCCACCGTCAATCGCCTGTGCAACGGGCATCGACGCATGAGCG
TTGCCGAGGCCAATCTGTTTGCCGATCTGTTCGAAACGACCGCCGACTTTTGGCTAAACCTGCAGGCGGCACACGATCGC
TGGGAAGCCAGACAGGCCGATGCGCAGCGTGTGCGGCTGCGGCCAATCAAAGAAATACTGGGACGCAATATCACTCATGC
ATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References