Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/VapC-VagC |
Location | 2684184..2684893 | Replicon | chromosome |
Accession | NZ_CP069318 | ||
Organism | Delftia lacustris strain R54 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | JQN63_RS12430 | Protein ID | WP_016453265.1 |
Coordinates | 2684184..2684630 (-) | Length | 149 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | JQN63_RS12435 | Protein ID | WP_203400733.1 |
Coordinates | 2684627..2684893 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JQN63_RS12410 | 2679782..2680996 | + | 1215 | WP_203400729.1 | ABC transporter permease | - |
JQN63_RS12415 | 2680998..2682143 | + | 1146 | WP_203400730.1 | ABC transporter permease | - |
JQN63_RS12420 | 2682207..2682836 | - | 630 | WP_203400731.1 | DUF4124 domain-containing protein | - |
JQN63_RS12425 | 2682915..2684120 | - | 1206 | WP_203400732.1 | MFS transporter | - |
JQN63_RS12430 | 2684184..2684630 | - | 447 | WP_016453265.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
JQN63_RS12435 | 2684627..2684893 | - | 267 | WP_203400733.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
JQN63_RS12440 | 2684918..2685889 | - | 972 | WP_203400734.1 | LysR family transcriptional regulator | - |
JQN63_RS12445 | 2685966..2686850 | + | 885 | WP_203400735.1 | amidohydrolase family protein | - |
JQN63_RS12450 | 2686877..2687872 | + | 996 | WP_016448238.1 | tripartite tricarboxylate transporter substrate binding protein | - |
JQN63_RS12455 | 2687896..2689527 | - | 1632 | WP_016448237.1 | gamma-glutamyltransferase family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 149 a.a. Molecular weight: 15880.46 Da Isoelectric Point: 8.1045
>T190133 WP_016453265.1 NZ_CP069318:c2684630-2684184 [Delftia lacustris]
MTRYLLDTNIASHIIKGDIPAVREQLVRVPMHQIAVSAVTQAELMYGVAKRGHPAGLSLRVTGFLARVEVLPWTAQVADA
YGHLRAACEATGITLASMDMMIAAHALLLQQQAAQAGERSVLVTRDRVFSRIPEPGLAIADWTTGPAG
MTRYLLDTNIASHIIKGDIPAVREQLVRVPMHQIAVSAVTQAELMYGVAKRGHPAGLSLRVTGFLARVEVLPWTAQVADA
YGHLRAACEATGITLASMDMMIAAHALLLQQQAAQAGERSVLVTRDRVFSRIPEPGLAIADWTTGPAG
Download Length: 447 bp
>T190133 NZ_CP091121:62002-62277 [Serratia ureilytica]
ATGGAGTTAAAATGGACGAGTAAGGCGCTACCGGATTTGGCGCGTTTGTTTGAGTTTCTTGCCTTGGCTAACCGCACTGC
GGCAGCGAATTCGGTGAAGGCCTTGGTCGCCGCGCCTAAAGCGTTGCTCGATAATCCTCGCCTGGGTGAAAGACTGGACG
AGTTTTTACCGCGGGAAGTGAGGCGTATTCTGGTCGGCCGTTATGAGATACGTTACCAGGTGCAGCCGGCAACGATTTAT
GTTCTGCGTATTTGGCATACCCGCGAAGAGCGATAG
ATGGAGTTAAAATGGACGAGTAAGGCGCTACCGGATTTGGCGCGTTTGTTTGAGTTTCTTGCCTTGGCTAACCGCACTGC
GGCAGCGAATTCGGTGAAGGCCTTGGTCGCCGCGCCTAAAGCGTTGCTCGATAATCCTCGCCTGGGTGAAAGACTGGACG
AGTTTTTACCGCGGGAAGTGAGGCGTATTCTGGTCGGCCGTTATGAGATACGTTACCAGGTGCAGCCGGCAACGATTTAT
GTTCTGCGTATTTGGCATACCCGCGAAGAGCGATAG
Antitoxin
Download Length: 89 a.a. Molecular weight: 10018.00 Da Isoelectric Point: 4.3846
>AT190133 WP_203400733.1 NZ_CP069318:c2684893-2684627 [Delftia lacustris]
VTQTAKLFTTGRSQAVRLPYEFRFEEKEVYIRRDPATGDVILSRRPDSWQEFFALDATTDVPADFMDTADRAQPESGRDP
FADEGSAR
VTQTAKLFTTGRSQAVRLPYEFRFEEKEVYIRRDPATGDVILSRRPDSWQEFFALDATTDVPADFMDTADRAQPESGRDP
FADEGSAR
Download Length: 267 bp
>AT190133 NZ_CP091121:61742-62002 [Serratia ureilytica]
ATGAATACGAAAGTCATCACCGCTCATGTCCCGCTGCCGTTGGCTGAAAAGGTGGATGAAATGGCCGCCAAACTTGACCG
TTCACGGGGATGGATAGTGAAGCAAGCCCTCGCCGCCTGGCTTGAGCAAGAGGAAGAGCGCCGTCGGTTAACGCTGGCGG
CGCTGGCCGATGTCGAACAGCAAAACGTTATCGATCATGAGTCGGTAGAAGCCTGGGCGGCCAGCCTGGACAGTGACGAG
CCGCTGCCGGTACCGCGCTGA
ATGAATACGAAAGTCATCACCGCTCATGTCCCGCTGCCGTTGGCTGAAAAGGTGGATGAAATGGCCGCCAAACTTGACCG
TTCACGGGGATGGATAGTGAAGCAAGCCCTCGCCGCCTGGCTTGAGCAAGAGGAAGAGCGCCGTCGGTTAACGCTGGCGG
CGCTGGCCGATGTCGAACAGCAAAACGTTATCGATCATGAGTCGGTAGAAGCCTGGGCGGCCAGCCTGGACAGTGACGAG
CCGCTGCCGGTACCGCGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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