Detailed information of TA system TA190095

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 3735023..3736749
• Replicon: chromosome
• Accession: NZ_CP069213
• Organism: Shewanella litorisediminis strain SMK1-12

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: JQC75_RS16555
• Protein ID: WP_203325115.1
• Coordinates: 3736099..3736749 (-)
• Length: 217 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: JQC75_RS16550
• Protein ID: WP_203325114.1
• Coordinates: 3735023..3736099 (-)
• Length: 359 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JQC75_RS16535	3730455..3730814	-	360	WP_203325111.1	hypothetical protein	-
JQC75_RS16540	3731027..3731749	-	723	WP_203325112.1	M48 family metallopeptidase	-
JQC75_RS16545	3731749..3735012	-	3264	WP_203325113.1	HsdR family type I site-specific deoxyribonuclease	-
JQC75_RS16550	3735023..3736099	-	1077	WP_203325114.1	macro domain-containing protein	Antitoxin
JQC75_RS16555	3736099..3736749	-	651	WP_203325115.1	DUF4433 domain-containing protein	Toxin
JQC75_RS16560	3736742..3738061	-	1320	WP_203325116.1	restriction endonuclease subunit S	-
JQC75_RS16565	3738054..3740825	-	2772	WP_203325117.1	type I restriction-modification system subunit M	-
JQC75_RS16570	3741184..3741375	-	192	WP_203325118.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (16-216)

Antitoxin

• Macro domain (18-130)

Sequences

Toxin

Protein

• Length: 217 a.a.
• Molecular weight: 25020.66 Da
• Isoelectric Point: 7.5888

>T190095 WP_203325115.1 NZ_CP069213:c3736749-3736099 [Shewanella litorisediminis]
MVNHYPNLNPQKALIWRIVHRDNLPWILDNGVHCKSAAVQDPNFVPIGNADLIDRRTHRGVPIAPGGVLSDYVPFYFTPF
SPMMYNIHTGRGEVTKRRNEDICILVSTLHKVHQLGLPFVFTDRHAYPPLARYFNRIESLHEIDWPLLQARNFQRNPDDP
EQIERYQAEALVHHHLPVAGLVGIICYTDNVKNTLDNQIQARGLTMDVRVMPQWYF

Nucleotide

• Length: 651 bp

>T190095 NZ_CP091081:847891-848301 [Enterobacter roggenkampii]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCTTTATTGCTCCACGGCCTGGTTGCGGC
CTTTGTGTTACTGATGCCGTGGCCGCTGAGCTATACGCCGCTGTGGCTGCTGCTACTTTCGTTTGTCGTTTTTGACAGCG
TACGCAGCCAGCGTCGCATTAATGCCCGTCAGGGAGAGATTAAATTACTGATGGATTCCCGCCTGCGCTGGCAGGGTAAA
GAGTGGGATATTCTCGGTATGCCCTGGATGCTCAACTGCGGCATGATGTTACGGTTACGCAAGGTGGACGGCGGGCGTTG
CCAGCATCTTTGGCTGGCGGCTGACAGTATGGATGCTGCCGAATGGCGAGACCTGCGCCGGATGCTGTTGCAACAGACGA
CGCAGGGGTAG

Antitoxin

Protein

• Length: 359 a.a.
• Molecular weight: 40530.50 Da
• Isoelectric Point: 6.0055

>AT190095 WP_203325114.1 NZ_CP069213:c3736099-3735023 [Shewanella litorisediminis]
MITYTQGNLLEARAEALVNTVNTVGVMGKGIALMFKERFGENFRLYVAACKAKEVQTGKMFVTDVYELDGPRWIVNFPTK
QHWRAKSQMAWVVEGLQDLRHFLIEQQVKSIAIPPLGAGNGGLEWDEVRKQIERALGDLDTDIQIFEPTLQYQNVAKRTG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERAIERYNPNDNPLKLQFVAHKYGPYANRLDHLLNNLDGSYLH
ADKRISDADPLDVIWFDDERKTLVQTYLNSEAKAYSQALEATAALIDGFESPFGMELLATVDWLLTREGVAPTVPALREG
LRHWRGGADAAARKDRLFDDRALGIALERLTQPATALM

Nucleotide

• Length: 1077 bp

>AT190095 NZ_CP091081:847644-847910 [Enterobacter roggenkampii]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGCCGTCGCGGCATGCGTGAACTTGATATTTCCATCATGCCTTT
CTTCGAATATGAGTATGACACCTTAAGCGACGACGATAAGCGTCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCGGATT
TATTCAACTGGCTGATGAACCACGGCAAACCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA