Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 3416409..3417512 Replicon chromosome
Accession NZ_CP069213
Organism Shewanella litorisediminis strain SMK1-12

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag JQC75_RS15080 Protein ID WP_203324856.1
Coordinates 3416409..3417149 (-) Length 247 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag JQC75_RS15085 Protein ID WP_203324857.1
Coordinates 3417150..3417512 (-) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JQC75_RS15055 3411813..3413582 - 1770 WP_203324851.1 alkaline phosphatase D family protein -
JQC75_RS15060 3413782..3414201 + 420 WP_203324852.1 CBS domain-containing protein -
JQC75_RS15065 3414250..3414939 - 690 WP_203324853.1 LrgB family protein -
JQC75_RS15070 3414939..3415370 - 432 WP_203324854.1 CidA/LrgA family protein -
JQC75_RS15075 3415474..3416382 + 909 WP_203324855.1 LysR family transcriptional regulator -
JQC75_RS15080 3416409..3417149 - 741 WP_203324856.1 RES family NAD+ phosphorylase Toxin
JQC75_RS15085 3417150..3417512 - 363 WP_203324857.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
JQC75_RS15090 3417754..3418407 + 654 WP_203324858.1 oxygen-insensitive NAD(P)H nitroreductase -
JQC75_RS15095 3418547..3419197 + 651 WP_203324859.1 DnaJ domain-containing protein -
JQC75_RS15100 3419357..3420103 + 747 WP_203324860.1 thiol:disulfide interchange protein DsbA/DsbL -
JQC75_RS15105 3420452..3421789 + 1338 WP_203324861.1 Na+/H+ antiporter NhaC family protein -
JQC75_RS15110 3421818..3422510 + 693 WP_203324862.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(54-198)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(5-65)


Sequences

Toxin        


Download         Length: 247 a.a.        Molecular weight: 28049.94 Da        Isoelectric Point: 5.8379

>T190094 WP_203324856.1 NZ_CP069213:c3417149-3416409 [Shewanella litorisediminis]
MDLLSIPAECIDLPYEGSCYRLVESQEEAATLSLVDNFDEQMLLESLLDGAKPPYREGTAHLHYLLKTPFRYPPLRHGSR
FGTRLMPSFFYGSESAQTCLTEVAYYRFIFLQDMAVPYQGVLHSEHMMFRVLLSAVRCADLTRIADGTLQQQLTHGEDYR
FTQALGQQLLDRHCQLIRSYSAREPGGVNLAVADPGVMASGPLDQTYWICQLEPARLAFTERGRGHLPRYYEVEAFYREG
RLPRPA

Download         Length: 741 bp

>T190094 NZ_CP091081:c255231-254929 [Enterobacter roggenkampii]
ATGAAGGAGATTGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAACTTAAAAGATCGACGAGCGAAGACCATTATCGC
TTCCCGCCTCTTTCGGTTGGCAAATGGCTTAGCGGGCGACGTTAAACCCGTGGGAGAAGGTATAAGTGAGCTAAGGATCC
ACTTTGGTCCGGGCTACAGGATCTATTTTAAAGACCAGGGCAATTACATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTGATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 12973.94 Da        Isoelectric Point: 10.2284

>AT190094 WP_203324857.1 NZ_CP069213:c3417512-3417150 [Shewanella litorisediminis]
MSAIAKPTASGVLFKAFIHACQALELTNAEASHIIGVNPSTLSRNAANGFKPESKQGELQLQLVRLYRSLYALAGGQQDF
MRHWLNSPNHALGGTPRELVKSVVGLVSVNQYLDAMRGKV

Download         Length: 363 bp

>AT190094 NZ_CP091081:c254922-254635 [Enterobacter roggenkampii]
ATGCATAAATTAACACCTTACGATCCCGCCAACGCGTTGGTGGATGACGAGGAAATCGCCGTGTTTATCGCTGATGCACT
AGAAACAGGCGACTCGACATATATCGCTAAAGCCCTTGGTGTTGTCGCGCGAGCCAAAGGCATATCGAACATTTCACAGC
AAACCGGTTTATCACGTGAGCAGCTTTATCGGTCATTCAGTGATAAAGGAAACCCAACGCTCAAAACCACGCTCGCGGTC
ATGAAAGCATTGGGTTTTGGGCTAACGCTCAAACACGCCGGGGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References