Detailed information of TA system TA190093

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 936336..936981
• Replicon: chromosome
• Accession: NZ_CP069213
• Organism: Shewanella litorisediminis strain SMK1-12

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: JQC75_RS04130
• Protein ID: WP_203326215.1
• Coordinates: 936556..936981 (+)
• Length: 142 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: JQC75_RS04125
• Protein ID: WP_203327117.1
• Coordinates: 936336..936575 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JQC75_RS04100	932041..932847	+	807	WP_203326210.1	prolipoprotein diacylglyceryl transferase	-
JQC75_RS04105	932847..933641	+	795	WP_203326211.1	thymidylate synthase	-
JQC75_RS04110	933764..934939	+	1176	WP_203326212.1	Na+/H+ antiporter NhaA	-
JQC75_RS04115	934936..935319	+	384	WP_203326213.1	hypothetical protein	-
JQC75_RS04120	935319..936227	+	909	WP_203326214.1	transcriptional activator NhaR	-
JQC75_RS04125	936336..936575	+	240	WP_203327117.1	succinate dehydrogenase assembly factor 2	Antitoxin
JQC75_RS04130	936556..936981	+	426	WP_203326215.1	hypothetical protein	Toxin
JQC75_RS04135	936956..938563	-	1608	WP_203326216.1	L-aspartate oxidase	-
JQC75_RS04140	938751..939329	+	579	WP_011758991.1	RNA polymerase sigma factor RpoE	-
JQC75_RS04145	939384..939983	+	600	WP_203326217.1	anti-sigma factor	-
JQC75_RS04150	939994..940932	+	939	WP_203326218.1	MucB/RseB C-terminal domain-containing protein	-
JQC75_RS04155	940929..941408	+	480	WP_203326219.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-133)

Antitoxin

• Flavinator of succinate dehydrogenase (4-74)

Sequences

Toxin

Protein

• Length: 142 a.a.
• Molecular weight: 16179.84 Da
• Isoelectric Point: 8.2673

>T190093 WP_203326215.1 NZ_CP069213:936556-936981 [Shewanella litorisediminis]
VDVRRLNFSLSASKDQYFSVVILWALFLTSFLAWPANLPIPVFAFQLLTAGAVSGFFIYSLWRLKGWRWQFGLCDNGDLD
DSEGRHRVRRAWVMPLACVLLIKKESGQGRLLFVFADMLEDGSYRDLCRLLLSINARDLES

Nucleotide

• Length: 426 bp

>T190093 NZ_CP091081:c254922-254635 [Enterobacter roggenkampii]
ATGCATAAATTAACACCTTACGATCCCGCCAACGCGTTGGTGGATGACGAGGAAATCGCCGTGTTTATCGCTGATGCACT
AGAAACAGGCGACTCGACATATATCGCTAAAGCCCTTGGTGTTGTCGCGCGAGCCAAAGGCATATCGAACATTTCACAGC
AAACCGGTTTATCACGTGAGCAGCTTTATCGGTCATTCAGTGATAAAGGAAACCCAACGCTCAAAACCACGCTCGCGGTC
ATGAAAGCATTGGGTTTTGGGCTAACGCTCAAACACGCCGGGGATTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9135.56 Da
• Isoelectric Point: 4.5658

>AT190093 WP_203327117.1 NZ_CP069213:936336-936575 [Shewanella litorisediminis]
MSIARVRWACRRGMLELDVLFQPFVENHYEALSDEQKAVFVRLLACEDPELFAWFMGHEQCPDPELADMVVTVRGRPAP

Nucleotide

• Length: 240 bp

>AT190093 NZ_CP091081:c255231-254929 [Enterobacter roggenkampii]
ATGAAGGAGATTGTTCAGACAGAATCCTTCCGACGCTGGGAGCAAAACTTAAAAGATCGACGAGCGAAGACCATTATCGC
TTCCCGCCTCTTTCGGTTGGCAAATGGCTTAGCGGGCGACGTTAAACCCGTGGGAGAAGGTATAAGTGAGCTAAGGATCC
ACTTTGGTCCGGGCTACAGGATCTATTTTAAAGACCAGGGCAATTACATCATCGTGCTGTTATGTGGTGGTGACAAAAGC
AGCCAGGCCAGAGACATACTGATGGCAAAAATGCTGAGCAATGTATCCCAATGGCAGGAGTGA