Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 2887285..2887850 Replicon chromosome
Accession NZ_CP069195
Organism Vibrio diabolicus strain SLV18

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag JOS67_RS13745 Protein ID WP_203346704.1
Coordinates 2887285..2887680 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag JOS67_RS13750 Protein ID WP_005397970.1
Coordinates 2887680..2887850 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JOS67_RS13735 2883079..2885169 - 2091 WP_203347274.1 YjbH domain-containing protein -
JOS67_RS13740 2886104..2886522 - 419 Protein_2504 IS110 family transposase -
JOS67_RS13745 2887285..2887680 - 396 WP_203346704.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
JOS67_RS13750 2887680..2887850 - 171 WP_005397970.1 hypothetical protein Antitoxin
JOS67_RS13755 2888566..2888727 - 162 WP_203346705.1 thrombospondin type 3 repeat-containing protein -
JOS67_RS13760 2888749..2889180 - 432 WP_203346706.1 hypothetical protein -
JOS67_RS13765 2889223..2890458 - 1236 WP_065275047.1 type II toxin-antitoxin system HipA family toxin -
JOS67_RS13770 2890451..2890726 - 276 WP_065274105.1 helix-turn-helix domain-containing protein -
JOS67_RS13775 2891289..2892635 - 1347 WP_203346707.1 ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - ugd 2859745..2908940 49195


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(1-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14335.42 Da        Isoelectric Point: 3.8306

>T190065 WP_203346704.1 NZ_CP069195:c2887680-2887285 [Vibrio diabolicus]
MDIICFPFERVIEINSFILATEPGMQGEVDIPKLQGALGRIDNAIAYDGLEDVFDIAAKYAASIAIAHALPDANKRTGLM
VALEYLSLNEFEIVIDNALLADAVRDLLLGVLTEADFADILYAQYTEGLER

Download         Length: 396 bp

>T190065 NZ_CP091067:c6557534-6557352 [Pseudomonas sp. BC42]
ATGCGCAGTCGGGAGATGATCGGCAAGATTGAGGCGGATGGTTGGTACCTGATTGCCGTGAAGGGCAGTCACCATCAGTA
CAAGCATCCCTGGAAACCAGGGCGCGTCACTTTCAAGCATCCGGATGCGGAACTGCCCAGGGGCACGCTCAACAGCATCT
TGAAACAGGCGGGCTTGAAATGA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6314.48 Da        Isoelectric Point: 11.4763

>AT190065 WP_005397970.1 NZ_CP069195:c2887850-2887680 [Vibrio diabolicus]
MSKDLSAYGVPQVKRPKVKATKQLDLSGMQGRQIVRSEAKLALRTHRKTFTKLADM

Download         Length: 171 bp

>AT190065 NZ_CP091067:c6557322-6556921 [Pseudomonas sp. BC42]
ATGAAATTCCCGGTGGTTCTGCACAAGGATGCCGACTCTGAATACGGGGTGATCGTTCCGGATGTGCCGGGCTGTTACTC
CGCTGGTCACACGGTGTCCCTGGCGTTCGAGAACGTGAAGGAGGCGTTGTCCCTGCATTACGCAGGGCTGGTGGCCGATG
GCGAGCCTCTGCCGCAGGTGCACGAGATCGATGAGCACCTGGACAACCCCGACTACGCCGGGGGTGTATGGGGCGTGGTG
GAGTTCGACGTGACGCCGTATTTCGGCAAGTCGGTGCGCTTCAATGCCACCCTGCCGGAACACCTGCTGGAGCGCATCGA
TCAGACGGTCAAGCGTGACCAGCGCTACAACTCGCGTTCCGGGTTCCTGGCCGCCGCGGCGCTGCGCGAACTGTCGGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References