Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2009528..2009673 Replicon chromosome
Accession NZ_CP069170
Organism Klebsiella pneumoniae strain KPWX136

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2009564..2009666 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2009528..2009673 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JLH18_RS09855 2004658..2006718 + 2061 WP_004151449.1 oligopeptidase B -
JLH18_RS09860 2006722..2007381 - 660 WP_002911407.1 exodeoxyribonuclease X -
JLH18_RS09865 2007460..2007690 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JLH18_RS09870 2007803..2008177 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JLH18_RS09875 2008181..2009050 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
JLH18_RS09880 2009067..2009405 + 339 WP_002911404.1 YebY family protein -
- 2009528..2009673 - 146 - - Antitoxin
- 2009564..2009666 + 103 - - Toxin
JLH18_RS09885 2010041..2010184 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JLH18_RS09890 2010289..2011257 - 969 WP_004151446.1 VirK/YbjX family protein -
JLH18_RS09895 2011414..2012067 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JLH18_RS09900 2012064..2012255 - 192 WP_002911395.1 YebW family protein -
JLH18_RS09905 2012353..2012592 - 240 WP_002911393.1 YebV family protein -
JLH18_RS09910 2012708..2014141 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T190016 NZ_CP069170:2009564-2009666 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT190016 NZ_CP069170:c2009673-2009528 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References