Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1883416..1884107 Replicon chromosome
Accession NZ_CP069161
Organism Paludibacterium paludis strain BCRC 80514

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JNO50_RS08485 Protein ID WP_189536733.1
Coordinates 1883416..1883805 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JNO50_RS08490 Protein ID WP_189536735.1
Coordinates 1883802..1884107 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNO50_RS08470 1879819..1880487 + 669 WP_189536965.1 hypothetical protein -
JNO50_RS08475 1880858..1881826 + 969 Protein_1662 IS481 family transposase -
JNO50_RS08480 1882175..1883137 - 963 Protein_1663 IS5 family transposase -
JNO50_RS08485 1883416..1883805 + 390 WP_189536733.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JNO50_RS08490 1883802..1884107 + 306 WP_189536735.1 DNA-binding transcriptional regulator Antitoxin
JNO50_RS08495 1884438..1884704 + 267 WP_189536737.1 flagellar biosynthesis protein FliQ -
JNO50_RS08500 1884714..1885484 + 771 WP_189536739.1 flagellar biosynthetic protein FliR -
JNO50_RS08505 1885487..1886548 + 1062 WP_189536741.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -
JNO50_RS08510 1886567..1888630 + 2064 WP_189536743.1 flagellar biosynthesis protein FlhA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-120)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-89)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14174.27 Da        Isoelectric Point: 9.8214

>T190009 WP_189536733.1 NZ_CP069161:1883416-1883805 [Paludibacterium paludis]
MHIYKTRQFGKWAGKEGLSDSVLAAAVAEMERGLIDADLGGHVVKKRVALPGRGKSGGARTLLAYRLADRAFFVYGFAKN
ERDNIDDKELKALKLLASTLLRWTEQQLAHALEEGALLPVNPDVQRGES

Download         Length: 390 bp

>T190009 NZ_CP091061:327908-328276 [Klebsiella pneumoniae]
ATGACGCTGCAGATTATCTCAGCGGAAGAGATAATACTGTTTCACGACAGGCTGCTCCGCGTCACGCCTGGCGTTGCCGG
TATGCCCGATCCGGGGCGTGCCGAAGCGATAATGTATAGGGTGCTAAACAAAATTGAATATGAAGGTGTGACAGACGTGT
GGCGACTCGCTGCGATGCATCTGCTGGCGATTTCTCGCGGTCATATATTTAATGATGGTAATAAGCGTACGGCACTGTTT
ATCACCCTGCTTTTTTTAAAGCGAAATGGAATTATATTGCCAGCGAATCCAGACTTCGTCGGCATGACCGTCGAGGCAGC
AGCAGGGCAACTTACCCTGGAACAGATTGTCGCGCGTTTGCGTGGATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11339.04 Da        Isoelectric Point: 7.8628

>AT190009 WP_189536735.1 NZ_CP069161:1883802-1884107 [Paludibacterium paludis]
MTSRLLETLHETAREFAEIGLVDAQTMREFDAACLPPVKNFTADEIKNLRLRCRASQAVFAAYLNTSPSTVQKWERGDKH
PNGPSLKLLNLVERKGLEVLA

Download         Length: 306 bp

>AT190009 NZ_CP091061:327690-327911 [Klebsiella pneumoniae]
ATGAGAACGGTTAACTATAGCGAAGCCCGGCAAAATCTGGCCGATGTGCTGGAAAGCGCAGTGACAGGTGTACCTGTGAC
CATTACCCGTCGTGGGCATAAATCTGCAGTCATCATTAGTGCAGAAGAGTTTGAACGCTACCAGGCGGCCAGAATGGATG
ATGAGTTCGCGGCTATCATGGCGGTTCATGGTGATGAGATCAGGGAGCTTGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References