Detailed information of TA system TA190008

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1614939..1615840
• Replicon: chromosome
• Accession: NZ_CP069161
• Organism: Paludibacterium paludis strain BCRC 80514

Toxin (Protein)

• Gene name: PrcT
• Uniprot ID: -
• Locus tag: JNO50_RS07295
• Protein ID: WP_189535562.1
• Coordinates: 1614939..1615382 (-)
• Length: 148 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JNO50_RS07300
• Protein ID: WP_189535564.1
• Coordinates: 1615379..1615840 (-)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JNO50_RS07280	1610150..1611007	+	858	WP_189535556.1	hypothetical protein	-
JNO50_RS07285	1611024..1612538	+	1515	WP_189535557.1	SCO family protein	-
JNO50_RS07290	1612672..1614933	+	2262	WP_189535559.1	hypothetical protein	-
JNO50_RS07295	1614939..1615382	-	444	WP_189535562.1	RES family NAD+ phosphorylase	Toxin
JNO50_RS07300	1615379..1615840	-	462	WP_189535564.1	DUF2384 domain-containing protein	Antitoxin
JNO50_RS07305	1615950..1616795	-	846	WP_189535632.1	3-deoxy-8-phosphooctulonate synthase	-
JNO50_RS07310	1617081..1617593	+	513	WP_189535565.1	GNAT family N-acetyltransferase	-
JNO50_RS07315	1617599..1619176	-	1578	WP_189535567.1	glycosyltransferase family 39 protein	-
JNO50_RS07320	1619259..1620446	-	1188	WP_189535570.1	citrate synthase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (4-139)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (101-150)

Sequences

Toxin

Protein

• Length: 148 a.a.
• Molecular weight: 16258.77 Da
• Isoelectric Point: 6.2133

>T190008 WP_189535562.1 NZ_CP069161:c1615382-1614939 [Paludibacterium paludis]
VIAWRISNYADLNGLGGLHAEGRWHFAGRPIVYLADHSASAMLEMLVHCELRTLPASFQLLRVEIPDDCLLDLDPGELEA
GWQARPHLTRGIGDAWLEQAPSAVLRVPSALTVDGRNLLLNPVHPDAARCRILDVLRAPLDPRLRPL

Nucleotide

• Length: 444 bp

>T190008 NZ_CP091060:c6137-5832 [Klebsiella pneumoniae]
ATGCAGTTTAAGGTTTATGCCTATAAAAGAGAGAGCCGCTATCGTCTGTTCGTGGATGTGCAGAGTGACATCATCGATAC
CCCCGGGCGACGGATGGTGATCCCGCTGGCCAGCGCCCGGCTGCTGTCGGATAAGGTTTCCTGTGAACTCTATCCGGTGG
TGCACATCGGGGATGAAAGCTACCGCCTGATGACCACGGACATGGCCAGCGTCACGTCCTCCGTCACCGGGGAGGAAGTG
GCCGATCTCAGCCACCGGGAAAATGACATCAAAAATGCGATAAACCTGATGTTCTGGGGAATTTGA

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 16931.34 Da
• Isoelectric Point: 9.8432

>AT190008 WP_189535564.1 NZ_CP069161:c1615840-1615379 [Paludibacterium paludis]
MTGTVFRRGTTHRTPARAARYTRLSKLIGHSVHSDLDVATCVAQGVEPILIDHLTREGLTRKELEFVIPARTLAHRIARK
ESLSRDESERGVRIANLLVLAEQVLGGAQAATDWLRHPLVRFGGATPLETARTEQGARLVENLLTQIDEGYFA

Nucleotide

• Length: 462 bp

>AT190008 NZ_CP091060:c6357-6139 [Klebsiella pneumoniae]
ATGAAGCAGCGCATCACTGTCACCATAGACAGCGACAGTTATCAGTTACTGAAATCCGCAGACGTCAATATCTCCGCCCT
GGTGAACAGGGCCATGCAGAATGAGGCCCGTCGTCTGCGTTCCGAACGCTGGCAGGCTGAAAATCAGGAAGGGATGGCCG
AGGTTGCCCGCTTTATTGAGATGAACGGTTCATTCGCCGACGAAAACAGGGACTGGTGA