Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 781601..782261 Replicon chromosome
Accession NZ_CP069159
Organism Citrobacter sp. R56

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JM656_RS03775 Protein ID WP_203360065.1
Coordinates 781848..782261 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JM656_RS03770 Protein ID WP_162380161.1
Coordinates 781601..781867 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JM656_RS03745 776801..778234 - 1434 WP_203360063.1 6-phospho-beta-glucosidase -
JM656_RS03750 778356..779084 - 729 WP_203361212.1 MurR/RpiR family transcriptional regulator -
JM656_RS03755 779137..779448 + 312 WP_203361211.1 N(4)-acetylcytidine aminohydrolase -
JM656_RS03760 779611..780270 + 660 WP_192613408.1 hemolysin III family protein -
JM656_RS03765 780364..781344 - 981 WP_203360064.1 tRNA-modifying protein YgfZ -
JM656_RS03770 781601..781867 + 267 WP_162380161.1 FAD assembly factor SdhE Antitoxin
JM656_RS03775 781848..782261 + 414 WP_203360065.1 protein YgfX Toxin
JM656_RS03780 782329..782850 - 522 WP_192613405.1 flavodoxin FldB -
JM656_RS03785 782963..783859 + 897 WP_192613404.1 site-specific tyrosine recombinase XerD -
JM656_RS03790 783883..784596 + 714 WP_203360066.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JM656_RS03795 784602..786335 + 1734 WP_203360067.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16483.53 Da        Isoelectric Point: 11.3186

>T189994 WP_203360065.1 NZ_CP069159:781848-782261 [Citrobacter sp. R56]
VVLWQSDLRVSWRAQWLSLLLHGLVAALILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINTRQGEIKLLMDGRLRWQGL
EWVIQRAPWMLKTGMMLRLRSDSGRRQHLWLAADSMDEKEWRELRRVMLQQTEQEKH

Download         Length: 414 bp

>T189994 NZ_CP091050:c134249-133779 [Klebsiella pneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
CTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACAGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGACAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAATTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10544.06 Da        Isoelectric Point: 5.1599

>AT189994 WP_162380161.1 NZ_CP069159:781601-781867 [Citrobacter sp. R56]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT189994 NZ_CP091050:c134689-134246 [Klebsiella pneumoniae]
ATGAAAACTTTTAGTTTGTCCTCAAGTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
TGTAGCGCTCCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGTGAACCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCAACCACATTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTTATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAGGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAAACTGGAGCCTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References