Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 851632..852115 Replicon chromosome
Accession NZ_CP069157
Organism Morganella morganii strain DSM 30164

Toxin (Protein)


Gene name relE Uniprot ID J7TMG3
Locus tag JL661_RS03845 Protein ID WP_004237651.1
Coordinates 851888..852115 (+) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag JL661_RS03840 Protein ID WP_225310119.1
Coordinates 851632..851904 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL661_RS03835 (JL661_03835) 846789..851423 + 4635 WP_062771823.1 hemagglutinin repeat-containing protein -
JL661_RS03840 (JL661_03840) 851632..851904 + 273 WP_225310119.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
JL661_RS03845 (JL661_03845) 851888..852115 + 228 WP_004237651.1 type II toxin-antitoxin system YafQ family toxin Toxin
JL661_RS03850 (JL661_03850) 852418..853902 + 1485 WP_004237652.1 C69 family dipeptidase -
JL661_RS03855 (JL661_03855) 853968..854420 - 453 WP_004237653.1 NfeD family protein -
JL661_RS03860 (JL661_03860) 854417..855355 - 939 WP_032099238.1 SPFH domain-containing protein -
JL661_RS03865 (JL661_03865) 855411..856268 - 858 WP_015422944.1 co-chaperone YbbN -
JL661_RS03870 (JL661_03870) 856328..857113 - 786 WP_062771820.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-74)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(2-78)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 9069.63 Da        Isoelectric Point: 9.9416

>T189990 WP_004237651.1 NZ_CP069157:851888-852115 [Morganella morganii]
MARTIERSSQFKKDYKREVKGIYRMMLNDSLQNILNILVNDLPIPEKYADHPLKGNWRTFRDCHLYPDLILIYKK

Download         Length: 228 bp

>T189990 NZ_CP091048:c4843855-4842938 [Klebsiella pneumoniae]
ATGGATATACAGGCGCCTTATTATCGGCAGGTTGCTCTGCTAATGCAGGTTTTACCCTATGTTGCTGTCGAACGGGAATT
TGCGCTGAAAGGTGGCACTGCAATCAATCTCTTTATCCGCGATTTCCCTCGATTATCGGTGGATATCGACCTCGCCTGGG
TGCCCCTGGAAAGCAGAGCCATCGCTTTACCTCATATACGGGATGCGCTTGCACGTATTGCCGCCAATCTGCAACAACAG
GCAGGTATGAGCGCTGTATTACAAGCTAATCGTTCAGATGAGATGCGTGTCATTGTTACTACCGATAGCGCGCAAATAAA
GATAGAGGTTTCACCGGTCGCCCGGGGAACATTATATCCACCACAGGAGCGAGAAGTGGTGGGGGCGGTAGAGGACGTTT
TTGGCTATGCCAGCCTTCCAGTGGTTTCGTTGCCTGACCTCTACGGTGGAAAATTATGCGCGGCGCTGGATCGCCAGCAT
CCCAGAGATTTTTATGACGTGAAATTACTTCTTGATGCGCAGGAGCTTGACCGTCCCATTTTCAATGGGTTTATCGCGTA
TTTACTGAGCCATAATCGGCCTCTGGCTGAAGTGCTGAGTCCTCGCTGGAAAGATATTGCTGAACCTTTTTACCGTGAAT
TCAGCGGGATGACATTTGAGACGATAGCCCTGGAGGAACTGACAGCAGTCCCCAACAGGATGATTGCTGCGTTAAAATCC
TGTTTCACACAACAGGATGTCGATTTTTTACTGTCATTTAAACGAGGCGAACCAGACTGGCGTTTAGCGCCGGAAATGCG
TATTCAGGATTTGCCTGCCGTGCAGTGGAAATTGCGCAATATTCATCAGATGCCAGCGATAAAACGCGCTGAGTCATTAG
ATAAACTGGAAAAGGTGCTGGCCGAGTGGCGCAGTTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10103.75 Da        Isoelectric Point: 5.1746

>AT189990 WP_225310119.1 NZ_CP069157:851632-851904 [Morganella morganii]
VEYVRAKIDPKLKAEAIETLESMGLTVSDAIRMLMIQIVEQKAMPFCVKSTQYRHAARIRAAIEELECGKGKKFDSISDL
MADLQDGKDD

Download         Length: 273 bp

>AT189990 NZ_CP091048:c4844619-4843861 [Klebsiella pneumoniae]
ATGGCAACAAAATTAAACTGGCTGCTGCAAAACAGCGCTCCCGGAGATGTGATCCTTCAGTCCTGGTTAAGCCAGCATGC
CATCTCTCCCTCTCTGGCCTTTAAATACGCGCAAAGTGGCTGGTTAAAAAAAAGAGGCAACGGCGTATATGCGCGTGCGG
GACGTGAGCCGGAGTGGAACGATGCATTAGCATGTTTGCAAAATCAGCTTGCCGCTCCGGTGTATGTTGCGGGGCTCAGT
AGCTTAGTCTGGCAGGGCCGTTCACACTATCTACAGCTAAAACAAAACCAGTGCTGGCTTAGTGTGGAAAATAAAGCGCT
GCTGCCGAAATGGTTCAGGGAATTCCCGGGTGTGGAGTGGATAGTCATATCGGGGAAAAAACTGCCGGTGCTGGATGATA
GATACCGTGTAACGCTTGATATAAAAGGGAAAAAACTCATCGGCAGTGCGCCAGAACTGGCTGCTTACGAGTTGCTGAGC
GCGGTGCCGGGGACCCTCTCATTTAACCACGCTGCAGAGCTTTTCCAGGGGCTGGTTAATCTTAATCCTCGTAAAGTAGA
GTATCTTCTTTCCGTCAGCCAGTCCGTGCAGGCCAAGCGTTTGTATCTCTTCTTCGCCAGTTTTTACGAGCATGGCTGGC
TCAAACGAATCGATAGCCAAAAAATCGATCTGGGAGCGGGCAAGCGGCAAATCGTGGAAAATGGAAAGTTCAATGCTCAA
TACCAAATCACAGTGCCTGAACGCTTTCAAAAGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB J7TMG3

Antitoxin

Source ID Structure

References