189900

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4683422..4683785 Replicon chromosome
Accession NZ_CP069085
Organism Xanthomonas campestris pv. campestris strain BJSJQ20200612

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JM952_RS20620 Protein ID WP_011270059.1
Coordinates 4683422..4683556 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JM952_RS20625 Protein ID WP_011038999.1
Coordinates 4683633..4683785 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JM952_RS20600 (JM952_20635) 4678687..4680339 - 1653 WP_172973909.1 M28 family metallopeptidase -
JM952_RS20605 (JM952_20640) 4680503..4681447 - 945 WP_172973853.1 MBL fold metallo-hydrolase -
JM952_RS20610 (JM952_20645) 4681531..4682820 - 1290 WP_172973854.1 tryptophan--tRNA ligase -
JM952_RS20615 (JM952_20650) 4682980..4683189 - 210 WP_011038998.1 CsbD family protein -
JM952_RS20620 (JM952_20655) 4683422..4683556 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JM952_RS20625 (JM952_20660) 4683633..4683785 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JM952_RS20630 (JM952_20665) 4683896..4684819 - 924 Protein_4004 arginase -
JM952_RS20635 (JM952_20670) 4685133..4685594 + 462 WP_011039001.1 roadblock/LC7 domain-containing protein -
JM952_RS20640 (JM952_20675) 4685677..4686036 + 360 WP_011039002.1 hypothetical protein -
JM952_RS20645 (JM952_20680) 4686139..4687056 + 918 WP_011039003.1 hypothetical protein -
JM952_RS20650 (JM952_20685) 4687053..4687595 + 543 WP_011039004.1 GTPase -
JM952_RS20655 (JM952_20690) 4687930..4688613 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T189900 WP_011270059.1 NZ_CP069085:c4683556-4683422 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T189900 NZ_CP091024:c3946192-3945815 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGAAGGCATCGCGCTGCCCGTCTCCCGTCACCGTCTGGCAGACACTACTCAC
CCGACTGCTGGACCAGCACTACGGCCTCACGCTGAATGACACACCGTTCGCTGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGGATTTCACTGTGTGACGCGGTGAACTTTCTTGTTGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGAATTC
AGTGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCCGGGCGACTGGCCTGATGACCCGCGA
CAATTACCGAACGGTAAATAACATTACCCTGGGTAAGTATCAGGAGGCGAAACGATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT189900 WP_011038999.1 NZ_CP069085:c4683785-4683633 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT189900 NZ_CP091024:c3946643-3946275 [Escherichia coli]
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGACGACAATCACGACCGCTCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAAGGGAACCGGTTGCATTACCTTGCAGACCGTGCCGGTATCAGAGGCCGGT
TCAGCGACGCGGATGCGTACCATCTGGACCAAGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCAGTTG
TGGCTACGTTTATATGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References