189898

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4559260..4559623 Replicon chromosome
Accession NZ_CP069084
Organism Xanthomonas campestris pv. campestris strain GSXT20191014

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag JOA57_RS19730 Protein ID WP_011270059.1
Coordinates 4559260..4559394 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag JOA57_RS19735 Protein ID WP_011038999.1
Coordinates 4559471..4559623 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JOA57_RS19710 (JOA57_19715) 4554524..4556176 - 1653 WP_043877841.1 M28 family metallopeptidase -
JOA57_RS19715 (JOA57_19720) 4556341..4557285 - 945 WP_068574725.1 MBL fold metallo-hydrolase -
JOA57_RS19720 (JOA57_19725) 4557369..4558658 - 1290 WP_029629069.1 tryptophan--tRNA ligase -
JOA57_RS19725 (JOA57_19730) 4558818..4559027 - 210 WP_011038998.1 CsbD family protein -
JOA57_RS19730 (JOA57_19735) 4559260..4559394 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
JOA57_RS19735 (JOA57_19740) 4559471..4559623 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
JOA57_RS19740 (JOA57_19745) 4559734..4560657 - 924 WP_011039000.1 arginase -
JOA57_RS19745 (JOA57_19750) 4560971..4561432 + 462 WP_237349589.1 roadblock/LC7 domain-containing protein -
JOA57_RS19750 (JOA57_19755) 4561515..4561874 + 360 WP_011039002.1 hypothetical protein -
JOA57_RS19755 (JOA57_19760) 4561977..4562894 + 918 WP_237349590.1 hypothetical protein -
JOA57_RS19760 (JOA57_19765) 4562891..4563433 + 543 WP_012439507.1 GTPase -
JOA57_RS19765 (JOA57_19770) 4563768..4564451 + 684 WP_011039005.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T189898 WP_011270059.1 NZ_CP069084:c4559394-4559260 [Xanthomonas campestris pv. campestris]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T189898 NZ_CP091024:3747280-3747498 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT189898 WP_011038999.1 NZ_CP069084:c4559623-4559471 [Xanthomonas campestris pv. campestris]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT189898 NZ_CP091024:3746880-3747254 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References