Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 128530..129560 Replicon chromosome
Accession NZ_CP069004
Organism Sulfitobacter mediterraneus strain SC1-11

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag JNX03_RS00570 Protein ID WP_203210568.1
Coordinates 128985..129560 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag JNX03_RS00565 Protein ID WP_203212077.1
Coordinates 128530..128988 (+) Length 153 a.a.

Genomic Context

JNX03_RS00540JNX03_RS00545JNX03_RS00555JNX03_RS00560JNX03_RS00565JNX03_RS00570JNX03_RS00580JNX03_RS00585JNX03_RS00590JNX03_RS00595JNX03_RS00550JNX03_RS00575JNX03_RS00600
Location: 123538..125208 (1671 bp)
Type: Others
Protein ID: WP_203210564.1
Location: 125400..126437 (1038 bp)
Type: Others
Protein ID: WP_203210565.1
Location: 127473..128336 (864 bp)
Type: Others
Protein ID: WP_203210566.1
Location: 128333..128509 (177 bp)
Type: Others
Protein ID: WP_203210567.1
Location: 128530..128988 (459 bp)
Type: Antitoxin
Protein ID: WP_203212077.1
Location: 128985..129560 (576 bp)
Type: Toxin
Protein ID: WP_203210568.1
Location: 130458..130712 (255 bp)
Type: Others
Protein ID: WP_203212078.1
Location: 130981..131283 (303 bp)
Type: Others
Protein ID: WP_058260762.1
Location: 131276..132496 (1221 bp)
Type: Others
Protein ID: WP_203210570.1
Location: 132804..133001 (198 bp)
Type: Others
Protein ID: WP_035262952.1
Location: 126441..126881 (441 bp)
Type: Others
Protein ID: WP_203212076.1
Location: 129615..130211 (597 bp)
Type: Others
Protein ID: WP_203210569.1
Location: 133265..134551 (1287 bp)
Type: Others
Protein ID: WP_203210571.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
JNX03_RS00540123538..125208+1671WP_203210564.1urocanate hydratase-
JNX03_RS00545125400..126437+1038WP_203210565.1aromatic ring-hydroxylating dioxygenase subunit alpha-
JNX03_RS00550126441..126881-441WP_203212076.1hypothetical protein-
JNX03_RS00555127473..128336+864WP_203210566.1hypothetical protein-
JNX03_RS00560128333..128509+177WP_203210567.1hypothetical protein-
JNX03_RS00565128530..128988+459WP_203212077.1helix-turn-helix domain-containing proteinAntitoxin
JNX03_RS00570128985..129560+576WP_203210568.1PIN domain-containing proteinToxin
JNX03_RS00575129615..130211-597WP_203210569.1hypothetical protein-
JNX03_RS00580130458..130712+255WP_203212078.1helix-turn-helix domain-containing protein-
JNX03_RS00585130981..131283+303WP_058260762.1helix-turn-helix domain-containing protein-
JNX03_RS00590131276..132496+1221WP_203210570.1type II toxin-antitoxin system HipA family toxin-
JNX03_RS00595132804..133001+198WP_035262952.1hypothetical protein-
JNX03_RS00600133265..134551-1287WP_203210571.1calmodulin-binding protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--127176..18440657230


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(11-115)

Antitoxin

Helix-turn-helix domain, group 17

(83-131)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21087.12 Da        Isoelectric Point: 4.4836

>T188833 WP_203210568.1 NZ_CP069004:128985-129560 [Sulfitobacter mediterraneus]
MSDYADRFTALIDANVLACAMRRNIILSLAEAGFFRPRWSDRIMDETAGAIAKITKGGADTNKQRSAMERAFPEACVTGY
AGLEAGLELPDPDDRHVLAAAITTSAQVIVTENLKDFPSEALVPFDIDAISADEFISDAIELDPLAAVVALRKMRERFKN
PDMDAEALLQRIKARKLFQTAEILHEYVELL

Download         Length: 576 bp

>T188833 NZ_CP090575:956824-957003 [Staphylococcus epidermidis]
ATGGCGAACAAAAAAGATTCCAAATTAAATTATCATGAAGAAGAAAATGCTATGGTTACCGACTTAGATGATTTAAAAGA
ATTAGGAAAAGAAATGGAACAGATTTCACAGGAAAATGATGAAGAAAAATTAAATCAATCTCATGATAACGAAGTTCGTT
CAGATTTAAAAAAACAGTAA

Antitoxin


Download         Length: 153 a.a.        Molecular weight: 16874.35 Da        Isoelectric Point: 4.9003

>AT188833 WP_203212077.1 NZ_CP069004:128530-128988 [Sulfitobacter mediterraneus]
MQAKEAFAERLPDQVEIENADSLRRILASQVNGDEAVELSLALGKKQIEPVTLAPALAASLMELLRLVSSGRGFRMIPVD
AELTTQQAADLLNVSRPHLVKLLEEGEIAFFKTGRHRRVKAADLFEYKKKRDSDRSDALSDLAAMDMENDLL

Download         Length: 459 bp

>AT188833 NZ_CP090575:956201-956800 [Staphylococcus epidermidis]
ATGGCAATGAATTTTAAAGTATTTGATAATAGTGAAAAAGTAGCAGAATATACTGCAGATATTCTACGTAAGCAATTTAA
TAATAATCCAACTACTATTGCAGGATTTCATTTGAGCAAAGAACATGCACCAGTGTTTGATGAACTTAAGAAAAATGTAG
AAAATCATACAGTTGATTTCAGTCAAATAAATATTTTAGATTATGATGATAATCATTCTTATTATGAGGCTTTGGGTGTG
CCAACAGGCCAAATTTATTCCATTTCTTACGAAAATGATGCAATTGACTTTATCTCAGATAAGATTAAGACTAAAGAAAA
TAAAGGCAAACTGACAATGCAAGTCCTTACGATTGATGAAAATGGTAAACTTGACATTAGCGTTCGTCAAGGTTTGATGG
AAGCTAGAGAAATTTTCTTAGTTATTACTGGTGCTAATAAACGCGATATGGTAGAAAAACTTTACCGTGAAAATGGTAAG
ACTAGTTTTGAACCATCGGATTTAAAAGCACACCGTATGGTCAATGTTATCTTAGATAAAGAAGCGGCTGCAGGCTTACC
TGAAGACGTAAAAGAGTACTTCACTGCACGTTTTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
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References