Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | spoIISABC/SpoIISA-SpoIISB |
| Location | 1304680..1305596 | Replicon | chromosome |
| Accession | NZ_CP068982 | ||
| Organism | Bacillus subtilis strain pb2441 | ||
Toxin (Protein)
| Gene name | spoIISA | Uniprot ID | O34853 |
| Locus tag | JNE32_RS06865 | Protein ID | WP_003244695.1 |
| Coordinates | 1304850..1305596 (-) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | spoIISB | Uniprot ID | G4EXD8 |
| Locus tag | JNE32_RS06860 | Protein ID | WP_003232646.1 |
| Coordinates | 1304680..1304850 (-) | Length | 57 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JNE32_RS06825 (1301546) | 1301546..1301872 | + | 327 | WP_029727046.1 | XkdW family protein | - |
| JNE32_RS06830 (1301869) | 1301869..1302033 | + | 165 | WP_014479563.1 | XkdX family protein | - |
| JNE32_RS06835 (1302077) | 1302077..1302916 | + | 840 | WP_029727045.1 | phage-like element PBSX protein XepA | - |
| JNE32_RS06840 (1302969) | 1302969..1303238 | + | 270 | WP_015252265.1 | hemolysin XhlA family protein | - |
| JNE32_RS06845 (1303251) | 1303251..1303514 | + | 264 | WP_014479566.1 | phage holin | - |
| JNE32_RS06850 (1303527) | 1303527..1304420 | + | 894 | WP_029727044.1 | N-acetylmuramoyl-L-alanine amidase | - |
| JNE32_RS06855 (1304457) | 1304457..1304594 | - | 138 | WP_119899277.1 | three component toxin-antitoxin-antitoxin system antitoxin SpoIISC | - |
| JNE32_RS06860 (1304680) | 1304680..1304850 | - | 171 | WP_003232646.1 | three component toxin-antitoxin-antitoxin system antitoxin SpoIISB | Antitoxin |
| JNE32_RS06865 (1304850) | 1304850..1305596 | - | 747 | WP_003244695.1 | toxin-antitoxin-antitoxin system toxin SpoIISA | Toxin |
| JNE32_RS06870 (1305706) | 1305706..1306707 | - | 1002 | WP_003232642.1 | inorganic phosphate transporter | - |
| JNE32_RS06875 (1306720) | 1306720..1307337 | - | 618 | WP_003218470.1 | DUF47 domain-containing protein | - |
| JNE32_RS06880 (1307613) | 1307613..1308929 | - | 1317 | WP_015252262.1 | serine/threonine exchanger | - |
| JNE32_RS06885 (1309317) | 1309317..1310267 | + | 951 | WP_003232637.1 | VOC family protein | - |
| JNE32_RS06890 (1310376) | 1310376..1310471 | + | 96 | Protein_1294 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 29061.50 Da Isoelectric Point: 4.6191
>T188807 WP_003244695.1 NZ_CP068982:c1305596-1304850 [Bacillus subtilis]
MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPTSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQNYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG
MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPTSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHMYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQNYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG
Download Length: 747 bp
>T188807 NZ_CP090568:c2760526-2760137 [Xanthomonas citri pv. malvacearum]
ATGCTTGATACCAACACCGTGAGCCATCTCGTCAAAAGCCATCCGGCTGTCTCTCGACGGGTCATTGAAGTGCCTATGAC
TGCGCTATGTATGTCCGCAATTACCGGTGGGGAGCTGATGTTCGGCTTGGCTAAGGTGCCAGACGCCAAACGCCTTCAGC
AAGCCGTCATGGAACTCCTGCGGCGCGTGGATGTGCTGCCTTGGGATGGCGCGGTAATGGAGCGTTACGGAAGCGTAAGA
GCGGACCTAGAAAAGCAAGGTAAAGCGCTTGGGTCGCTCGACATGCTTATCGCAGCACATGCACTGGAAACGGATTCTGT
CCTCGTTACCAATGACGCCGCATTTAGTCGTGTTGTTGGTTTGACCGTGGAAGATTGGACACGCAGCTAA
ATGCTTGATACCAACACCGTGAGCCATCTCGTCAAAAGCCATCCGGCTGTCTCTCGACGGGTCATTGAAGTGCCTATGAC
TGCGCTATGTATGTCCGCAATTACCGGTGGGGAGCTGATGTTCGGCTTGGCTAAGGTGCCAGACGCCAAACGCCTTCAGC
AAGCCGTCATGGAACTCCTGCGGCGCGTGGATGTGCTGCCTTGGGATGGCGCGGTAATGGAGCGTTACGGAAGCGTAAGA
GCGGACCTAGAAAAGCAAGGTAAAGCGCTTGGGTCGCTCGACATGCTTATCGCAGCACATGCACTGGAAACGGATTCTGT
CCTCGTTACCAATGACGCCGCATTTAGTCGTGTTGTTGGTTTGACCGTGGAAGATTGGACACGCAGCTAA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6654.72 Da Isoelectric Point: 11.0203
>AT188807 WP_003232646.1 NZ_CP068982:c1304850-1304680 [Bacillus subtilis]
MERAFQNRCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA
MERAFQNRCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKKA
Download Length: 171 bp
>AT188807 NZ_CP090568:c2760795-2760535 [Xanthomonas citri pv. malvacearum]
GTGAGCCAAGTTGCCAAGCTGTTCATCAATGGCCGCAGCCAGGCAGTCCGCTTGCCTGCCGCCTATCGCTTTACCGAGAA
AGAGGTTTTCATTCGCCAAGACCCGGAGACCGGTGACGTCATCCTGTCTCGGAAGCCTGCAACGTGGGAGGACTTCTTTA
TCGCACTCAAGAGCGCAGATGTGCCTGCTAATTTTCTAGATGCCGCCGAGCGCAATCAGGGCACGCAGGACCGTGATCCT
TTTGCGGGATGGCGCGAATGA
GTGAGCCAAGTTGCCAAGCTGTTCATCAATGGCCGCAGCCAGGCAGTCCGCTTGCCTGCCGCCTATCGCTTTACCGAGAA
AGAGGTTTTCATTCGCCAAGACCCGGAGACCGGTGACGTCATCCTGTCTCGGAAGCCTGCAACGTGGGAGGACTTCTTTA
TCGCACTCAAGAGCGCAGATGTGCCTGCTAATTTTCTAGATGCCGCCGAGCGCAATCAGGGCACGCAGGACCGTGATCCT
TTTGCGGGATGGCGCGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|