Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 376013..376284 Replicon chromosome
Accession NZ_CP068820
Organism Escherichia coli strain RIVM_C029951

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 376143..376246 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 376013..376284 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNN41_RS02045 372568..373230 - 663 WP_000944256.1 exodeoxyribonuclease X -
JNN41_RS02050 373254..373910 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
JNN41_RS02055 374012..374242 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JNN41_RS02060 374381..374755 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JNN41_RS02065 374759..375631 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
JNN41_RS02070 375644..375985 + 342 WP_000976472.1 YebY family protein -
- 376013..376284 - 272 - - Antitoxin
- 376143..376246 + 104 - - Toxin
JNN41_RS02075 376381..377037 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
JNN41_RS02080 377038..377229 - 192 WP_001296140.1 YebW family protein -
JNN41_RS02085 377334..377570 - 237 WP_001295499.1 DUF1480 family protein -
JNN41_RS02090 377688..379127 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 305689..392124 86435


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T188448 NZ_CP068820:376143-376246 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT188448 NZ_CP068820:c376284-376013 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References