Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2248255..2248523 Replicon chromosome
Accession NZ_CP068816
Organism Escherichia coli strain RIVM_C028724

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2248383..2248485 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2248255..2248523 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNN36_RS10415 2244807..2245469 - 663 WP_000944256.1 exodeoxyribonuclease X -
JNN36_RS10420 2245493..2246149 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
JNN36_RS10425 2246252..2246482 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JNN36_RS10430 2246621..2246995 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JNN36_RS10435 2246999..2247871 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
JNN36_RS10440 2247884..2248225 + 342 WP_000984819.1 YebY family protein -
- 2248255..2248523 - 269 - - Antitoxin
- 2248383..2248485 + 103 - - Toxin
JNN36_RS10445 2248620..2249276 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
JNN36_RS10450 2249277..2249468 - 192 WP_001296140.1 YebW family protein -
JNN36_RS10455 2249573..2249809 - 237 WP_001295499.1 DUF1480 family protein -
JNN36_RS10460 2249927..2251366 - 1440 WP_001298454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T188328 NZ_CP068816:2248383-2248485 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT188328 NZ_CP068816:c2248523-2248255 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References