Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-HTH_XRE |
Location | 3470430..3471135 | Replicon | chromosome |
Accession | NZ_CP068813 | ||
Organism | Escherichia coli strain RIVM_C029033 |
Toxin (Protein)
Gene name | relE | Uniprot ID | S1F406 |
Locus tag | JNN62_RS16885 | Protein ID | WP_000539521.1 |
Coordinates | 3470430..3470816 (+) | Length | 129 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | JNN62_RS16890 | Protein ID | WP_001280945.1 |
Coordinates | 3470806..3471135 (+) | Length | 110 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JNN62_RS16865 | 3466434..3467060 | + | 627 | WP_001295292.1 | glutathione S-transferase GstB | - |
JNN62_RS16870 | 3467057..3468172 | - | 1116 | WP_000555051.1 | aldose sugar dehydrogenase YliI | - |
JNN62_RS16875 | 3468283..3468666 | - | 384 | WP_000497137.1 | biofilm formation regulator BssR | - |
JNN62_RS16880 | 3468879..3470204 | + | 1326 | WP_000049367.1 | 30S ribosomal protein S12 methylthiotransferase RimO | - |
JNN62_RS16885 | 3470430..3470816 | + | 387 | WP_000539521.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
JNN62_RS16890 | 3470806..3471135 | + | 330 | WP_001280945.1 | DNA-binding transcriptional regulator | Antitoxin |
JNN62_RS16895 | 3471205..3472533 | - | 1329 | WP_001550887.1 | GGDEF domain-containing protein | - |
JNN62_RS16900 | 3472541..3474889 | - | 2349 | WP_001550886.1 | EAL domain-containing protein | - |
JNN62_RS16905 | 3475067..3475978 | - | 912 | WP_001236042.1 | glutathione ABC transporter permease GsiD | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 129 a.a. Molecular weight: 14293.45 Da Isoelectric Point: 9.9296
>T188245 WP_000539521.1 NZ_CP068813:3470430-3470816 [Escherichia coli]
MGVYKARRFSQSTKKLGIHDKVLMAAAEEVMQGIWEADLGSGVIKKRLPLQQGKSGGARTIIFFKSANHVFFYDGWSKSG
LSSKGTKEIEDDELAAYKKMANAFLAFSNKQIEDLIETGFLIEVKNER
MGVYKARRFSQSTKKLGIHDKVLMAAAEEVMQGIWEADLGSGVIKKRLPLQQGKSGGARTIIFFKSANHVFFYDGWSKSG
LSSKGTKEIEDDELAAYKKMANAFLAFSNKQIEDLIETGFLIEVKNER
Download Length: 387 bp
>T188245 NZ_CP090381:2895378-2895953 [Achromobacter deleyi]
GTGAGGCATTCGCCGTTCACCGCCGTCTACGACGCCTGCGTCCTGTATCCCGCACCTCTGCGCGATTTCCTGATGTGGCT
CGGGCTGTCGGGAAGGTTTCGCGCGCGATGGAGTCCGCAGATCCACGATGAATGGAAACGCAATCTGCTAAGCAACCGAG
GCGACCTTACGTCCGAGCAACTGGACCGCACTTCCGCCTTGATGGACCGGGCAATTCCAGATGGCTTGGTTACCGGCCAC
GAGACTCTCATCGCCGGGCTGAGTCTGCCGGATCCCGATGATCGCCACGTACTGGCCGCGGCAATCCGCTGCAGCGCGAG
CGTGATCGTCACGTTCAACCAAAAGGATTTTCCGGCCGCTGCGCTCGACCCCTACGGCATCGAAGCGCAGCACCCGGACG
AGTTCGTCGAAAACCTGTTCGATCTGGACCAGGCTGCAGTCGTCTCCGCCGCCCAGCGCCAGCGCGCACAACTCAAGAAT
CCGACAATGGATGTGAATCGTTATCTGGACGTGCTTCTGCGACAGGGACTGGTTCAGACTGTCAAAGCACTGAGTACCTA
TCAGGCTATTTTGTGA
GTGAGGCATTCGCCGTTCACCGCCGTCTACGACGCCTGCGTCCTGTATCCCGCACCTCTGCGCGATTTCCTGATGTGGCT
CGGGCTGTCGGGAAGGTTTCGCGCGCGATGGAGTCCGCAGATCCACGATGAATGGAAACGCAATCTGCTAAGCAACCGAG
GCGACCTTACGTCCGAGCAACTGGACCGCACTTCCGCCTTGATGGACCGGGCAATTCCAGATGGCTTGGTTACCGGCCAC
GAGACTCTCATCGCCGGGCTGAGTCTGCCGGATCCCGATGATCGCCACGTACTGGCCGCGGCAATCCGCTGCAGCGCGAG
CGTGATCGTCACGTTCAACCAAAAGGATTTTCCGGCCGCTGCGCTCGACCCCTACGGCATCGAAGCGCAGCACCCGGACG
AGTTCGTCGAAAACCTGTTCGATCTGGACCAGGCTGCAGTCGTCTCCGCCGCCCAGCGCCAGCGCGCACAACTCAAGAAT
CCGACAATGGATGTGAATCGTTATCTGGACGTGCTTCTGCGACAGGGACTGGTTCAGACTGTCAAAGCACTGAGTACCTA
TCAGGCTATTTTGTGA
Antitoxin
Download Length: 110 a.a. Molecular weight: 11982.08 Da Isoelectric Point: 10.0101
>AT188245 WP_001280945.1 NZ_CP068813:3470806-3471135 [Escherichia coli]
MSDKLQMMLEDAKELNALGLMSDSEVDAIAVMVKAREVSARIAKVKSMTGEEIKAIRTRYGMSQSVLAHTMGMSKESVSK
WERNEIKPSGPALRILNTLAIKGPEVFAK
MSDKLQMMLEDAKELNALGLMSDSEVDAIAVMVKAREVSARIAKVKSMTGEEIKAIRTRYGMSQSVLAHTMGMSKESVSK
WERNEIKPSGPALRILNTLAIKGPEVFAK
Download Length: 330 bp
>AT188245 NZ_CP090381:2894914-2895381 [Achromobacter deleyi]
ATGCCTCACACCGCGCTGTCCAAAATGGTGCTGCCCGTCGAGCGCGAGGTAGAAGCGGCTGTGCAAGGCCAACGCGCCTT
GGCGGCCTACCTTGCAACCAGGTTCGAGACTCAAAGCATCCAGATTCTTGACGACCAGAACCAGGCCCACAACGTGGAGT
TGCCCACCTCGGCGCTGCGCCTGCTGGTGGATATCCTGGCGGAACTCGCCGACGGCAACGCCGTCCAGGTCGTCCCGATC
CATGCCGAGCTGACAACCCAGGAAGCCGCTGATCTTCTCAACGTTTCGCGGCCCCATATCGTCAAGCTGCTGGAAGAGGG
CCTGCTCCCATTCCACCGAACCGGCAAGCACCGCCGCGTGCGCTTCGCCGACCTGATGCAGTTCAAGGCTGAACGCGAGC
GCGCCAGCGAGCAAGCCATGGAAGAACTTGCCAGGCAGGCCCAGGAACTGGCCATGGGGTATGAGTGA
ATGCCTCACACCGCGCTGTCCAAAATGGTGCTGCCCGTCGAGCGCGAGGTAGAAGCGGCTGTGCAAGGCCAACGCGCCTT
GGCGGCCTACCTTGCAACCAGGTTCGAGACTCAAAGCATCCAGATTCTTGACGACCAGAACCAGGCCCACAACGTGGAGT
TGCCCACCTCGGCGCTGCGCCTGCTGGTGGATATCCTGGCGGAACTCGCCGACGGCAACGCCGTCCAGGTCGTCCCGATC
CATGCCGAGCTGACAACCCAGGAAGCCGCTGATCTTCTCAACGTTTCGCGGCCCCATATCGTCAAGCTGCTGGAAGAGGG
CCTGCTCCCATTCCACCGAACCGGCAAGCACCGCCGCGTGCGCTTCGCCGACCTGATGCAGTTCAAGGCTGAACGCGAGC
GCGCCAGCGAGCAAGCCATGGAAGAACTTGCCAGGCAGGCCCAGGAACTGGCCATGGGGTATGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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