Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2201663..2201934 Replicon chromosome
Accession NZ_CP068811
Organism Escherichia coli strain RIVM_C028568

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2201793..2201896 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2201663..2201934 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNN42_RS10510 2198218..2198880 - 663 WP_000944256.1 exodeoxyribonuclease X -
JNN42_RS10515 2198904..2199560 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
JNN42_RS10520 2199662..2199892 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JNN42_RS10525 2200031..2200405 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JNN42_RS10530 2200409..2201281 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
JNN42_RS10535 2201294..2201635 + 342 WP_000976472.1 YebY family protein -
- 2201663..2201934 - 272 - - Antitoxin
- 2201793..2201896 + 104 - - Toxin
JNN42_RS10540 2202031..2202687 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
JNN42_RS10545 2202688..2202879 - 192 WP_001296140.1 YebW family protein -
JNN42_RS10550 2202984..2203220 - 237 WP_001295499.1 DUF1480 family protein -
JNN42_RS10555 2203338..2204777 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2192490..2217774 25284


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T188168 NZ_CP068811:2201793-2201896 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT188168 NZ_CP068811:c2201934-2201663 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References