Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2264719..2264990 Replicon chromosome
Accession NZ_CP068808
Organism Escherichia coli strain RIVM_C018699

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2264849..2264952 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2264719..2264990 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNN47_RS10950 2261274..2261936 - 663 WP_000944256.1 exodeoxyribonuclease X -
JNN47_RS10955 2261960..2262616 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
JNN47_RS10960 2262718..2262948 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JNN47_RS10965 2263087..2263461 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JNN47_RS10970 2263465..2264337 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
JNN47_RS10975 2264350..2264691 + 342 WP_000976472.1 YebY family protein -
- 2264719..2264990 - 272 - - Antitoxin
- 2264849..2264952 + 104 - - Toxin
JNN47_RS10980 2265087..2265743 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
JNN47_RS10985 2265744..2265935 - 192 WP_001296140.1 YebW family protein -
JNN47_RS10990 2266040..2266276 - 237 WP_001295499.1 DUF1480 family protein -
JNN47_RS10995 2266394..2267833 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2194977..2280830 85853


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T188074 NZ_CP068808:2264849-2264952 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT188074 NZ_CP068808:c2264990-2264719 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References