Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
Location | 4481786..4482294 | Replicon | chromosome |
Accession | NZ_CP068801 | ||
Organism | Escherichia coli strain RIVM_C018220 |
Toxin (Protein)
Gene name | shpA | Uniprot ID | - |
Locus tag | JNN52_RS21745 | Protein ID | WP_001534843.1 |
Coordinates | 4482085..4482294 (-) | Length | 70 a.a. |
Antitoxin (Protein)
Gene name | shpB | Uniprot ID | A0A0V9L4L3 |
Locus tag | JNN52_RS21740 | Protein ID | WP_000063161.1 |
Coordinates | 4481786..4482088 (-) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JNN52_RS21725 | 4478314..4480464 | + | 2151 | WP_001366791.1 | pyruvate/proton symporter BtsT | - |
JNN52_RS21730 | 4480582..4480785 | + | 204 | WP_001534846.1 | YbdD/YjiX family protein | - |
JNN52_RS21735 | 4480796..4481752 | + | 957 | WP_001534845.1 | GTPase | - |
JNN52_RS21740 | 4481786..4482088 | - | 303 | WP_000063161.1 | BrnA antitoxin family protein | Antitoxin |
JNN52_RS21745 | 4482085..4482294 | - | 210 | WP_001534843.1 | BrnT family toxin | Toxin |
JNN52_RS21750 | 4482390..4483556 | + | 1167 | WP_001534841.1 | restriction endonuclease | - |
JNN52_RS21755 | 4483620..4485239 | + | 1620 | WP_001550561.1 | type I restriction-modification system subunit M | - |
JNN52_RS21760 | 4485229..4486539 | + | 1311 | WP_001534837.1 | restriction endonuclease subunit S | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 70 a.a. Molecular weight: 7952.17 Da Isoelectric Point: 4.9493
>T187883 WP_001534843.1 NZ_CP068801:c4482294-4482085 [Escherichia coli]
MVDYPKRDAISNINAIIVDTFLYIQLGMATMPMEFEWNANKAKSNRVKHGIRFEDAVLVLDDPQRTEPL
MVDYPKRDAISNINAIIVDTFLYIQLGMATMPMEFEWNANKAKSNRVKHGIRFEDAVLVLDDPQRTEPL
Download Length: 210 bp
>T187883 NZ_CP090094:c187674-187381 [Rhizobium leguminosarum]
ATGAGTTTTAAGCTTTCTGCCGATGCGGAAGAGGACATTATTGCGATCGCCGAGCAAGGTGTCCGTATGTTCGGGGCAGG
TCAGGCAAAGCGATACCACGATGAACTTTTCGCGTTATTTGATCTGATAGCTGTCAATCCACGCATCGCGCGCGAACGGG
ATGAGATTGATCCGCCTGTTAGAATTCATCCCTTCAAAGCGCATCTAGTCGTTTATCGGATCGAAGATGATGAGACAATT
TTTGTAATACGAATTCGCCACGCCCATGAAGATTGGGCAACTGATTCAATTTAG
ATGAGTTTTAAGCTTTCTGCCGATGCGGAAGAGGACATTATTGCGATCGCCGAGCAAGGTGTCCGTATGTTCGGGGCAGG
TCAGGCAAAGCGATACCACGATGAACTTTTCGCGTTATTTGATCTGATAGCTGTCAATCCACGCATCGCGCGCGAACGGG
ATGAGATTGATCCGCCTGTTAGAATTCATCCCTTCAAAGCGCATCTAGTCGTTTATCGGATCGAAGATGATGAGACAATT
TTTGTAATACGAATTCGCCACGCCCATGAAGATTGGGCAACTGATTCAATTTAG
Antitoxin
Download Length: 101 a.a. Molecular weight: 11600.10 Da Isoelectric Point: 9.4646
>AT187883 WP_000063161.1 NZ_CP068801:c4482088-4481786 [Escherichia coli]
MSMVKHKRGTSSTLDVQHEAELKVLANKFDEDIDYSDIPSSSDEQWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK
MSMVKHKRGTSSTLDVQHEAELKVLANKFDEDIDYSDIPSSSDEQWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLRDQNKK
Download Length: 303 bp
>AT187883 NZ_CP090094:c187913-187671 [Rhizobium leguminosarum]
ATGGCCACGATGAACGTATCTCTTCCAGGCCCGATGAAGGATTGGGTGGAGGCCCAGGCCAGGACCGGGCGATATTCTAA
TGCTAGCGACTACGTGCGCGACCTGATCCGACGCGACCAGACGCGAAACGACAAGATCGCCGCCATGCAAAGCTTCGTCG
AGGCCGGGCTCCAAAGTGGTGTCGGCATCCGATCAAAGGATGAACTCTTTGCTGAGGCGATAGCTCGTGCCAGCAAGTCA
TGA
ATGGCCACGATGAACGTATCTCTTCCAGGCCCGATGAAGGATTGGGTGGAGGCCCAGGCCAGGACCGGGCGATATTCTAA
TGCTAGCGACTACGTGCGCGACCTGATCCGACGCGACCAGACGCGAAACGACAAGATCGCCGCCATGCAAAGCTTCGTCG
AGGCCGGGCTCCAAAGTGGTGTCGGCATCCGATCAAAGGATGAACTCTTTGCTGAGGCGATAGCTCGTGCCAGCAAGTCA
TGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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