Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2250564..2250835 Replicon chromosome
Accession NZ_CP068801
Organism Escherichia coli strain RIVM_C018220

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2250694..2250797 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2250564..2250835 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JNN52_RS10855 2247119..2247781 - 663 WP_000944256.1 exodeoxyribonuclease X -
JNN52_RS10860 2247805..2248461 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein -
JNN52_RS10865 2248563..2248793 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JNN52_RS10870 2248932..2249306 + 375 WP_000168747.1 CopC domain-containing protein YobA -
JNN52_RS10875 2249310..2250182 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
JNN52_RS10880 2250195..2250536 + 342 WP_000976472.1 YebY family protein -
- 2250564..2250835 - 272 - - Antitoxin
- 2250694..2250797 + 104 - - Toxin
JNN52_RS10885 2250932..2251588 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
JNN52_RS10890 2251589..2251780 - 192 WP_001296140.1 YebW family protein -
JNN52_RS10895 2251885..2252121 - 237 WP_001295499.1 DUF1480 family protein -
JNN52_RS10900 2252239..2253678 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T187867 NZ_CP068801:2250694-2250797 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT187867 NZ_CP068801:c2250835-2250564 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References